Structural and luminescence properties of novel Eu-doped NaBaLaNbO phosphors with high quantum efficiency and excellent color purity for w-LED applications.

In this study, we report the successful synthesis and thorough characterization of Eu-doped NaBaLaNbO phosphors, targeting their application in white-light-emitting diodes (w-LEDs). The phosphors were synthesized using a high-temperature solid-state method, ensuring robust incorporation of Eu ions into the host lattice. Comprehensive analyses were performed, including X-ray diffraction (XRD), field emission scanning electron microscopy (FESEM), energy-dispersive X-ray (EDX) spectroscopy, Fourier transform infrared (FT-IR) spectroscopy and Raman spectroscopy, confirming the phase purity, crystallinity, morphology, and elemental composition of the phosphors.

Solitary Intracranial Plasmacytoma of the Brain Treated With Primary Radiation Therapy.

We present a rare case of a solitary intracranial plasmacytoma of the brain parenchyma in a 49-year-old female who presented with neck pain/headache, paresthesias, and auditory hallucinations. A workup revealed a solitary left parietal lobe brain lesion and a biopsy demonstrated a plasma cell infiltrate consistent with an extramedullary plasmacytoma. A complete workup for multiple myeloma was negative.

Overall survival in advanced hepatocellular carcinoma treated with concomitant systemic therapy and stereotactic body radiation therapy or systemic therapy alone.

Introduction: First-line systemic therapy (ST) options for advanced hepatocellular carcinoma (HCC) include tyrosine kinase inhibitors and immunotherapy (IO). Evolving data suggest prolonged overall survival (OS) when ST is combined with stereotactic body radiation therapy (SBRT), although evidence is significantly limited in HCC populations. We hypothesized that advanced HCC patients in the National Cancer Database (NCDB) would have improved OS when receiving ST+SBRT vs ST alone.

Survival in Metastatic Renal Cell Carcinoma Treated With Immunotherapy and Stereotactic Radiation Therapy or Immunotherapy Alone: A National Cancer Database Analysis.

Purpose: Immunotherapy (IO) has significantly improved outcomes in metastatic renal cell carcinoma (mRCC). Preclinical evidence suggests that responses to IO may be potentiated via immunomodulatory effects of stereotactic radiation therapy (SRT). We hypothesized that clinical outcomes from the National Cancer Database (NCDB) would demonstrate improved overall survival (OS) in patients with mRCC receiving IO + SRT versus IO alone.

Genomic-regions associated with cold stress tolerance in Asia-adapted tropical maize germplasm.

Maize is gaining impetus in non-traditional and non-conventional seasons such as off-season, primarily due to higher demand and economic returns. Maize varieties directed for growing in the winter season of South Asia must have cold resilience as an important trait due to the low prevailing temperatures and frequent cold snaps observed during this season in most parts of the lowland tropics of Asia. The current study involved screening of a panel of advanced tropically adapted maize lines to cold stress during vegetative and flowering stage under field conditions.

Lumino-structural properties of Dy activated NaBaLaNbO phosphors with enhanced internal quantum yield for w-LEDs.

With an intend to develop white light emitting phosphor, for w-LED application, a series of dysprosium (Dy) doped novel NaBaLaNbO phosphors were prepared using solid state reaction technique at 1300 °C. Their structural, morphological and vibrational spectroscopic analysis was performed. We illustrate the luminescence characteristics of the prepared phosphors for various Dy ion doping concentration.

Genome-wide association mapping in maize: status and prospects.

Unlabelled: Genome-wide association study (GWAS) provides a robust and potent tool to retrieve complex phenotypic traits back to their underlying genetics. Maize is an excellent crop for performing GWAS due to diverse genetic variability, rapid decay of linkage disequilibrium, availability of distinct sub-populations and abundant SNP information. The application of GWAS in maize has resulted in successful identification of thousands of genomic regions associated with many abiotic and biotic stresses.

Utilizing Hospital Formulary System in Nepal.

Since the early 1950s, for medication management, the hospital formulary system subsisted as a list of drugs into the supply chain management process in hospitals. With the advent of pharmacy practice services, the system now is more oriented towards the rational use of drugs taking into account the safety of therapy, cost-effectiveness, and uninterrupted availability of drugs to improve and reflect upon the clinical judgment of healthcare professionals. Though very few hospitals in Nepal have adopted hospital formulary system, the perfect practice is still skimpy.

Current Management and Progress in Radiotherapy for Small Cell Lung Cancer.

Radiotherapy (RT) and chemotherapy continue to be widely utilized in small cell lung cancer (SCLC) management. In most limited stage (LS)-SCLC cases, the standard initial therapy remains concurrent chemoradiotherapy (CRT), typically with an etoposide and platinum-based regimen. Hyperfractionated twice daily (BID) RT remains the standard of care, though conventional daily (QD) RT is now a viable alternative supported by randomized evidence.

Overall and chemotherapy-free survival following stereotactic body radiation therapy for abdominopelvic oligometastases.

Introduction: Limited data establish the efficacy and safety of SBRT in the abdominopelvic (AP) space, where SBRT delivery is challenging due to the proximity of radiosensitive luminal gastrointestinal (GI) organs. The aim of this study was to assess clinical outcomes in patients with AP OM treated with SBRT.

Methods: Eligible patients were those with OM (defined as metastases in ≤3 total sites) in the AP space (excluding liver) treated with SBRT.

A comparative study for surface dose evaluation in conventional treatment of carcinoma breast patients irradiated with Co-60 and 6 MV radiation beam.

Aim: In the present study, surface doses within the target area and contralateral breast (CLB) received during conventional treatment of carcinoma breast are evaluate and compared for treatment on two different beam energies, i.e., Co-60 γ-ray and 6 MV X-ray beams with thermoluminescent dosimeter, LiF:Mg, Ti (TLD-100).

Evaluation of positional accuracy of the Varian's exact-arm and retractable-arm support electronic portal imaging device using intensity-modulated radiotherapy graticule phantom.

Purpose: The aim of the present study was to compare the positional accuracy of varian's exact-arm (E-arm) and retractable-arm (R-arm) supporting electronic portal imaging device (EPID) systems (amorphous silicon flat-panel detector) using the intensity-modulated radiotherapy (IMRT) graticule phantom.

Materials And Methods: The known shifts of 0.5, 1.

Yield and kernel nutritional quality in normal maize and quality protein maize cultivars exposed to ozone.

Background: Tropospheric ozone (O ) is phytotoxic and therefore impacts global food security. In the present study yield responses and kernel quality traits of two maize cultivars [DHM117: normal maize (NM)] and [HQPM1: quality protein maize (QPM)] are investigated. Cultivars were exposed to two doses of elevated O , namely NFC + 15 and NFC + 30 ppb O above ambient level (NFC, non-filtered chambers) while filtered chambers served as control.

Genetic diversity of sweet corn inbreds using agro-morphological traits and microsatellite markers.

Assessment of genetic diversity is a pre-requisite to broaden the genetic background of cultivated base of sweet corn, an endosperm mutant of field corn that alters starch biosynthesis pathway in endosperm. In the current investigation, genetic divergence among 39 inbred lines was assessed on the basis of 14 agro-morphological traits, two quality parameters and 63 microsatellite markers, selected on the basis of their association with QTLs affecting kernel quality. The cluster analysis based on unweighted pair-group method using arithmetic averages for agro-morphological and quality traits grouped the 39 inbreds into three clusters with 5, 14 and 20 genotypes, respectively.

Current concepts on immunopathogenesis of hepatitis B virus infection.

Hepatitis B virus (HBV) infection is a leading cause of liver damage and hepatic inflammation. Upon infection, effective antiviral responses by CD8+ T cells, CD4+ T cells, Natural killer (NK) cells, and monocytes can lead to partial or complete eradication of the viral infection. To date, many studies have shown that the production of inhibitory cytokines such as Interleukin 10 (IL-10), Transforming growth factor beta (TGF-β), along with dysfunction of the dendritic cells (DCs), and the absence of efficient innate immune responses could lead to T cell exhaustion, development of persistent infection, and inability to eradicate the viral infection from liver.

The first report of two cases of fatal liver injury due to anti-tuberculosis drugs in the presence of alpha-1 antitrypsin deficiency.

Tuberculosis (TB) is a major global health problem. Awareness of liver injury due to anti-TB therapy is vital because fulminant hepatic failure is a devastating and often fatal condition without liver transplantation. Here, we report for the first time, two patients of fatal liver injury due to anti-TB drugs in the presence of alpha-1 antitrypsin deficiency.

Management of small-cell lung cancer with radiotherapy-a pan-Canadian survey of radiation oncologists.

Background: The management of small-cell lung cancer (sclc) with radiotherapy (rt) varies, with many treatment regimens having been described in the literature. We created a survey to assess patterns of practice and clinical decision-making in the management of sclc by Canadian radiation oncologists (ros).

Methods: A 35-item survey was sent by e-mail to Canadian ros.

Investigating the response of tropical maize (Zea mays L.) cultivars against elevated levels of O3 at two developmental stages.

Tropospheric ozone (O3) concentrations are rising in Indo-Gangetic plains of India, causing potential threat to agricultural productivity. Maize (Zea mays L.) is the third most important staple crop at global level after rice and wheat.

Assessment of growth and yield losses in two Zea mays L. cultivars (quality protein maize and nonquality protein maize) under projected levels of ozone.

Rapid industrialization and economic developments have increased the tropospheric ozone (O3) budget since preindustrial times, and presently, it is supposed to be a major threat to crop productivity. Maize (Zea mays L.), a C4 plant is the third most important staple crop at global level with a great deal of economic importance.

Effect of bioactive compounds extracted from euphorbious plants on hematological and biochemical parameters of Channa punctatus.

Channa punctatus was exposed to four different concentrations of Rutin, Taraxerol and Apigenin. Changes in some hematological parameters of Channa punctatus were assessed to determine the influence of these compounds on test fish. Fish were exposed to sublethal concentrations (80% of LC50 of 24h) of these compounds for one week.

Treatment outcomes of locally advanced oropharyngeal cancer: a comparison between combined modality radio-chemotherapy and two variants of single modality altered fractionation radiotherapy.

Purpose: To compare outcomes in patients with locally advanced oropharyngeal cancer treated with radio-chemotherapy (RT-CT), accelerated fractionation radiotherapy (AccRT), or hypofractionated radiotherapy (HypoRT).

Methods And Materials: Subjects were 321 consecutive patients with newly diagnosed oropharyngeal cancer, Stage III or IVA/B, treated between January 2001 and December 2005 at the BC Cancer Agency with RT-CT (n = 157), AccRT (n = 57), or HypoRT (n = 107). Outcomes examined were disease-specific survival (DSS), locoregional control (LRC), overall survival (OS), rate of G-tube use, and rate of hospitalization for acute complications.