A case of recurring acute exudative polymorphous vitelliform maculopathy successfully treated with intravitreal Ozurdex injection.

Introduction: We describe a case of acute exudative polymorphous vitelliform maculopathy (AEPVM) that recurred 9 years after the initial event. To the best of our knowledge, this is the first report of recurrent AEPVM showing recovery of retinal and retinal pigment epithelium (RPE) function and good visual outcome following treatment with intravitreal corticosteroid.

Case Description: A 45-year-old Caucasian woman first presented with AEVPM in 2009.

CRB1-Associated Retinal Dystrophies: Genetics, Clinical Characteristics, and Natural History.

Purpose: To analyze the clinical characteristics, natural history, and genetics of CRB1-associated retinal dystrophies.

Design: Multicenter international retrospective cohort study.

Methods: Review of clinical notes, ophthalmic images, and genetic testing results of 104 patients (91 probands) with disease-causing CRB1 variants.