Patient satisfaction and clinical outcomes with laser refractive surgery performed by surgeons in training.

Purpose: To evaluate the refractive error quality of life (RQL) improvement, patient satisfaction, and clinical results of laser refractive surgery performed by residents or fellows.

Setting: Department of Ophthalmology and Visual Sciences, University of Wisconsin, Madison, USA.

Design: Case series.

Beta2-adrenergic receptor signaling mediates corneal epithelial wound repair.

Purpose: Beta-adrenergic receptor (AR) antagonists are frequently prescribed ophthalmic drugs, yet previous investigations into how catecholamines affect corneal wound healing have yielded conflicting

Results: With the use of an integrated pharmacologic and genetic approach, the authors investigated how the beta-AR impacts corneal epithelial healing.

Methods: Migratory rates of cultured adult murine corneal epithelial (AMCE) cells and in vivo corneal wound healing were examined in beta2-AR(+/+) and beta2-AR(-/-) mice. Signaling pathways were evaluated by immunoblotting.