Recent Perspectives on Anticancer Potential of Coumarin Against Different Human Malignancies: An Updated Review.

Coumarins, a group of naturally occurring compounds, have been reported to demonstrate anticancer potential. These substances, distinguished by their combined benzene and α-pyrone rings, have been demonstrated to impact multiple cellular mechanisms essential for the initiation and advancement of cancer. These agents work in different ways that prevent different tumor cells from growing, spreading, and increasing.

Fungicide resistance in Fusarium species: exploring environmental impacts and sustainable management strategies.

The agricultural productivity and world-wide food security is affected by different phytopathogens, in which Fusarium is more destructive affecting more than 150 crops, now got resistance against many fungicides that possess harmful effects on environment such as soil health, air pollution, and human health. Fusarium fungicide resistance is an increasing concern in agricultural and environmental contexts, requiring a thorough understanding of its causes, implications, and management approaches. The mechanisms of fungicide resistance in Fusarium spp.

Fertigation with alpha-tocopherol enhances morphological, physiological, and antioxidant responses in radish (Raphanus sativus L.) under drought stress.

Water scarcity is a foremost environmental concern and is expected to hasten in the forthcoming years due to severe fluctuations in weather patterns worldwide. The present work was designed to explore the potential role of alpha-tocopherol (α-Toc), a form of vitamin E, on the morphological, physio-biochemical, and cellular antioxidant responses of two radish genotypes grown under drought conditions (38 ± 3% of field capacity). The individual and combined applications of α-Toc (100 ppm) were used as T0- Control, T1- Control + TF (TF-alpha-tocopherol), T2- Drought (D), and T3- D + TF with three replications.

The role of taxation in environmental sustainability in G-20 economies: A double dividend theoretical assessment.

This study analyses the influence of environmental taxes, renewable energy, economic growth, green innovation and financial development on environmental sustainability in G-20 countries from 1990 to 2022. To this end, the Method of Moments Quantile Regression (MMQR) was applied to obtain the reference results, complemented with Fully Modified Ordinary Least Square (FMOLS) and Driscoll-Kraay techniques to perform a comparative analysis. Our results confirm a negative relationship between environmental taxes and sustainability in all quantiles, although this relationship is only significant in the middle and upper quantiles.

The effect of mechanical milling for enhanced recycling Ti6Al4V powder from machining chips.

This study investigates the optimization of mechanical milling parameters to enhance the recycling of Ti6Al4V machining chips, addressing a significant challenge in sustainable materials processing. The influence of ball-to-powder ratio (BPR) and ball size distribution on powder characteristics, including crystallite size, particle size, and phase composition, was systematically examined. Key findings include a 30% reduction in crystallite size, with the smallest crystallite size of 51.

Exploring dihydropyrimidone derivatives as modulators of carbohydrate catabolic enzyme to mitigate diabetes.

Diabetes is a prevalent and serious metabolic disorder affecting millions globally, and it poses extensive health risks due to elevated blood glucose levels. One promising approach for managing diabetes is the inhibition of α-glucosidase, an enzyme that plays a crucial role in carbohydrate metabolism. Targeting α-glucosidase can help delay glucose absorption, thus controlling postprandial blood sugar spikes.

Recurrent Gastrointestinal Symptoms and Diagnosis of Superior Mesenteric Artery Syndrome.

This is a case of a young lady who was admitted multiple times with complaints of inability to digest food and abdominal pain. She had nausea and vomiting for long periods and was unable to tolerate orally. As she was unable to tolerate oral feeding and losing weight, she was started on nasogastric feed (NG feed) and later percutaneous endoscopic gastrostomy (PEG) tube feeding because NG feed was uncomfortable for the patient and did not alleviate the problem.

Does board gender diversity benefit for corporate ESG performance: Evidence from Germany.

More and more women have been engaged in public affairs in recent years. Due to the different perspectives and knowledge of female and male, female directors play more roles in corporate sustainable development, especially for corporate social, environmental and governance performance. This study uses panel data of 275 firms from 2010 to 2018 of German firms, to explore the impact of female directors on the board of corporate environmental, social and governance performance.

Antioxidant, anticancer, and anti-inflammatory potential of Moringa seed and Moringa seed oil: A comprehensive approach.

a widely recognized plant more commonly known as moringa, has obtained significant research interest in recent years due to its prospective physiological advantages, including its claimed ability to counteract carcinogenesis. The moringa plant has been found to possess bioactive components that exhibit promising anticancer activities against different human cancers, such as breast cancer, prostate cancer, pancreatic cancer, etc. The cytotoxic properties of moringa seed extracts on cancerous cells have also been provided in this paper along with other notable health benefits.

Congenital Diaphragmatic Hernia With Poor Clinical Outcome: Key Lessons To Be Learned.

Congenital diaphragmatic hernia (CDH) refers to the abnormal protrusion of abdominal contents (stomach, intestine) into the thoracic cavity, leading to the underdevelopment of the lungs (pulmonary hypoplasia). It is a critical neonatal condition that presents significant challenges in both diagnosis and management, especially in resource-limited countries. This case report describes a term female baby born via normal vaginal delivery to a mother with no prenatal care.

Connecting the dots: NETosis and the periodontitis-rheumatoid arthritis nexus.

Periodontitis (PD) is characterized by the host's inflammatory responses to microbial dental biofilm dysbiosis, potentially resulting in tooth loss if left untreated. Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease leading to synovial inflammation and destruction of joint cartilage and bone. The suggested association between PD and RA is based on the potential of chronic inflammation present in periodontitis, which could induce alterations in proteins through post-translational modifications, leading to the formation of citrullinated and carbamylated protein antigens.

A Review on Architecting Rationally Designed Metal-Organic Frameworks for the Next-Generation Li-S Batteries.

The modern era demands the development of energy storage devices with high energy density and power density. There is no doubt that lithium‒sulfur batteries (Li‒S) claim high theoretical energy density and have attracted great attention from researchers, but fundamental exploration and practical applications cannot converge to utilize their maximum potential. The design parameters of Li-S batteries involve various complex mechanisms, and their obliviousness has resulted in failure at the commercial level.

Enhancing Wheat Tolerance to Cadmium Stress through Moringa Leaf Extract Foliar Application.

Cadmium, a hazardous heavy metal prevalent in plants and soil, poses a significant threat to human health, particularly as approximately 60% of the global population consumes wheat, which can accumulate high levels of Cd through its roots. This uptake leads to the translocation of Cd to the shoots and grains, exacerbating the potential health risks. However, promising results have been observed with the use of moringa leaf extract (MLE) foliar spray in mitigating the adverse effects of Cd stress.

A recursive dynamic CGE approach to investigate environmental Kuznets curve.

The inverted U-shaped relationship between economic growth and environmental degradation is known as environmental Kuznets curve (EKC) and has been tested in many empirical studies since more than 3 decades. Technological change is one of the tools that can be used to examine the existence of EKC in CGE models. The objective is to extract EKC for G7 countries using a multi-regional CGE model and investigate the effects of some key factors affecting EKC using historical data for the period of 1861-2021.

Effects of Environment, Social, and Governance (ESG) Disclosures on ESG Scores: Investigating the Role of Corporate Governance for Publicly Traded Turkish Companies.

The world has experienced climate-related issues, which increase the importance of ESG disclosures and corporate governance (CG) of companies, which take place at the heart of economies. Therefore, improving ESG disclosures and CG practices becomes significant to combat climate change at the company level. Considering that Türkiye restructured ESG disclosures in 2022, this study investigates the role of CG on the nexus between ESG scores of publicly traded companies (PTC) and ESG reports.

Deciphering fungicide resistance in Phytophthora: mechanisms, prevalence, and sustainable management approaches.

The genus Phytophthora contains more than 100 plant pathogenic species that parasitize a wide range of plants, including economically important fruits, vegetables, cereals, and forest trees, causing significant losses. Global agriculture is seriously threatened by fungicide resistance in Phytophthora species, which makes it imperative to fully comprehend the mechanisms, frequency, and non-chemical management techniques related to resistance mutations. The mechanisms behind fungicide resistance, such as target-site mutations, efflux pump overexpression, overexpression of target genes and metabolic detoxification routes for fungicides routinely used against Phytophthora species, are thoroughly examined in this review.

Integrating international Chinese visualization teaching and vocational skills training: leveraging attention-connectionist temporal classification models.

The teaching of Chinese as a second language has become increasingly crucial for promoting cross-cultural exchange and mutual learning worldwide. However, traditional approaches to international Chinese language teaching have limitations that hinder their effectiveness, such as outdated teaching materials, lack of qualified instructors, and limited access to learning facilities. To overcome these challenges, it is imperative to develop intelligent and visually engaging methods for teaching international Chinese language learners.