Gut microbiota modulates weight gain in mice after discontinued smoke exposure.

Cigarette smoking constitutes a leading global cause of morbidity and preventable death, and most active smokers report a desire or recent attempt to quit. Smoking-cessation-induced weight gain (SCWG; 4.5 kg reported to be gained on average per 6-12 months, >10 kg year in 13% of those who stopped smoking) constitutes a major obstacle to smoking abstinence, even under stable or restricted caloric intake.