Background And Aims: To date, no epidemiological survey has estimated the prevalence of adolescents identifying as being in recovery. This is necessary for planning and identifying the needs of youth with current and remitted substance use disorders. This study estimated the prevalence of recovery status in a large statewide epidemiological survey administered between January and March 2020.
View Article and Find Full Text PDFBackground: Epidemiological surveys offer essential data on adolescent substance use. Nevertheless, the precision of these self-report-based surveys often faces mistrust from researchers and the public. We evaluate the efficacy of a direct method to assess data quality by asking adolescents if they were honest.
View Article and Find Full Text PDFIntroduction: In the United States, 19 states permit recreational use of cannabis, with 16 more permitting medical use (Marijuana Policy Project, 2021). Concerns remain about whether liberalized policies result in increased adolescent cannabis use. To date, limited evidence exists that the statewide prevalence of adolescent cannabis use increased in states with liberalized policies.
View Article and Find Full Text PDFAn in-depth knowledge of the molecular evolution of the peste des petits ruminants virus (PPRV) is critical for the success of the current global eradication program. For this reason, a molecular evolutionary analysis of PPRVs circulating in Bangladesh over a decade (2008-2020) was performed. The complete genome sequencing of three PPRV isolates from 2008 (BD2), 2015 (BD12) and 2017 (BD17) as well as full length nucleocapsid (N), matrix (M) and fusion (F) gene sequencing of seven more samples from 2015 to 2020 was performed.
View Article and Find Full Text PDFWe studied the sequential pathology of peste des petits ruminants (PPR) in Black Bengal goats and analyzed virus distribution in tissues and virus shedding following experimental infection with a Bangladeshi isolate of lineage IV PPR virus (PPRV). The early clinical signs like fever, depression, and ocular and nasal discharges first appeared at 4-7 days post-infection (dpi). Three out of eight inoculated goats died at 13, 15, and 18 dpi, and the rest were killed at different time points from 5 to 18 dpi.
View Article and Find Full Text PDFBackground: Traditionally isolation of peste des petits ruminant virus (PPRV) is performed in Vero cells that takes several blind passages before observing typical cytopathic effects (CPEs). As an alternate, researchers have been using lamb kidney (LK) cells but day-old lambs are difficult to obtain and requires animal sacrifice.
Objective: We established a primary goat kidney (GK) cell culture from the kidneys obtained at slaughter.
Background: Knowledge of sequential changes in haematobiochemical parameters of infected animals helps in the formulation of appropriate supportive therapy.
Objective: We investigated the sequential haematological and biochemical changes in peste des petits ruminants (PPR)-infected Black Bengal goats.
Methods: Goats were either infected with PPR virus (PPRV; n = 8) or sham infected with sterile phosphate-buffered saline (n = 4) via the intranasal route.
In Bangladesh, veterinarians often claim to reduce the mortality of natural peste des petits ruminants (PPR) outbreaks with the help of supportive fluid and electrolyte therapy. Information on haematological and biochemical parameters of PPR-infected goats, which is often altered because of associated tissue damages, is necessary to formulate the appropriate supportive therapy. This study determined the haematological and serum biochemical parameters of Black Bengal goats naturally infected with PPR virus.
View Article and Find Full Text PDFBackground: Early adolescence is developmental period when youth begin to shift exercise and physical activity patterns toward increased sedentary living. The major causes and contributing factors to this change are poorly understood. This study examines the relationship between sociodemographic factors, behavioral and family factors that influence physical activity patterns of middle grades students.
View Article and Find Full Text PDFObjective: To evaluate the current practice pattern of antibiotic prescription rate in viral respiratory tract infection diagnosed children among different specialty health care providers.
Methods: The study was a retrospective case review study where a random sample of 1200 child care visits coded as viral respiratory infections in primary care provider's office, convenient care clinic, or emergency room in 2006 were analyzed.
Results: Overall, the antibiotic prescription rate was 30%.
Heparin-binding protein 17/fibroblast growth factor-binding protein-1 (HBp17/FGFBP-1) is a secreted protein that releases immobilized fibroblast growth factor-2 (FGF-2) from the extracellular matrix and plays a critical role in FGF bioactivation. In the present study co-localization of FGF-2 and HBp17/FGFBP-1 was observed in oral tissues including normal mucosa, hyperplasia, dysplasia of different degrees and oral squamous cell carcinoma (OSCC). The expression score for HBp17/FGFBP-1, FGF-2 as well as vascular endothelial growth factor A (VEGF-A) became higher with the severity of epithelial dysplasia and was highest in severe dysplasia.
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