Endoscopic ultrasound-guided gallbladder drainage (EUS-GBD) with lumen apposing metal stent (LAMS) has emerged as an effective alternative to percutaneous cholecystostomy in managing acute cholecystitis patients with contraindications to open or laparoscopic cholecystectomy. Herein, the authors describe a case of a 69-year-old male who presented to interventional radiology with sepsis due to acute calculous cholecystitis and LAMS migration into the gallbladder. After stabilizing the patient with percutaneous cholecystostomy, percutaneous cholecysto-lithotripsy/lithectomy, cholecystoduodenal stenting, and LAMS retrieval were performed.
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