Publications by authors named "Shafie D"
Background: Heart failure (HF), or congestive Heart failure (CHF), is a heart disorder with a number of symptoms caused by the heart's inability to pump blood. Our aim in conducting this study is to investigate the adherence to dietary approaches to stop hypertension (DASH) diet components and the risk of HF in Iranian adult women and men.
Methods: In this hospital-based, case-control study, we included 340 participants (194 men and 146 women) aged 30-70 years who were recently (less than 6 months) diagnosed with HF.
Background: Heart failure (HF) is still associated with quite considerable mortality rates and usage of simple tools for prognosis is pivotal. We aimed to evaluate the effect of shock index (SI) and its derivatives (age SI (ASI), modified SI (MSI), and age MSI (AMSI)) on acute HF (AHF) clinical outcomes.
Methods: PubMed/Medline, Scopus and Web of science databases were screened with no time and language limitations till February 2024.
Article Synopsis
- * ACCS may not respond well to typical treatments like inotropes and fluids, making glucocorticoid administration crucial for survival, which emphasizes the importance of early detection of AI.
- * The study reviews case reports linking acute cardiomyopathies to AI and discusses possible mechanisms, urging physicians to consider AI as a possible cause in critically ill patients with cardiogenic shock.
Background: Acute kidney injury (AKI) and contrast-induced nephropathy (CIN) are common complications following percutaneous coronary intervention (PCI) or coronary angiography (CAG), presenting significant clinical challenges. Machine learning (ML) models offer promise for improving patient outcomes through early detection and intervention strategies.
Methods: A comprehensive literature search following PRISMA guidelines was conducted in PubMed, Scopus, and Embase from inception to June 11, 2024.
Objective: We examined the accuracy of novel anthropometric indices in predicting the progression of prediabetes to diabetes.
Subjects And Methods: This study was performed on the pre-diabetic sub-population from Isfahan Cohort Study (ICS). Participants were followed up from 2001 to 2013.
Article Synopsis
- * Anthracyclines, particularly doxorubicin, are effective in fighting tumors but can cause serious heart damage, known as cardiotoxicity.
- * Understanding how doxorubicin affects heart function is essential for creating new protective strategies against its harmful impacts on the cardiovascular system.
Background: Heart failure is a chronic and progressive disease where the heart muscle is unable to pump enough blood and oxygen to meet the body's needs. Oxidative stress and inflammation are key elements in the development and progression of heart failure. Astaxanthin, a carotenoid, has strong anti-inflammatory and antioxidant effects that may protect the cardiovascular system.
View Article and Find Full Text PDFArticle Synopsis
- Primary adrenal insufficiency (AI) presents with vague symptoms like fatigue and weight loss, but can also lead to severe cardiovascular issues such as cardiogenic shock.
- A 26-year-old man experienced vasopressor-resistant cardiogenic shock, which was eventually identified as stemming from an adrenal crisis linked to his history of Hashimoto's disease.
- Diagnosing AI in patients with cardiogenic shock can be critical, especially if they have a history of autoimmune diseases, since delays in treatment can have serious consequences.
Article Synopsis
- * The disease is characterized by granulomas, which initially show macrophage-lymphocytic infiltration and can progress to epithelioid cell formation and fibrosis, typically found in specific regions of the heart.
- * Improved diagnostic imaging techniques, such as CT and MRI, have enhanced the ability to diagnose cardiac sarcoidosis, and this article reviews the latest findings and insights from a multidisciplinary team.
Article Synopsis
- This guideline is Iran's first systematic approach for diagnosing and managing hyperlipidemia in adults, addressing key clinical questions with evidence-based recommendations.
- It sets specific thresholds for LDL-C (over 190 mg/dL) and triglycerides (over 500 mg/dL) to initiate drug treatment while emphasizing lifestyle changes as the primary intervention.
- Statins are recommended as the first-line medication, with additional options proposed for high levels, and targets for LDL-C (<130 mg/dL) and triglycerides (<200 mg/dL) are specified for adults without comorbidities.
Cardiovascular disease, specifically heart failure (HF), remains a significant concern in the realm of healthcare, necessitating the development of new treatments and biomarkers. The RNA family consists of various subgroups, including microRNAs, PIWI-interacting RNAs (piRAN) and long non-coding RNAs, which have shown potential in advancing personalized healthcare for HF patients. Recent research suggests that circular RNAs, a lesser-known subgroup of RNAs, may offer a novel set of targets and biomarkers for HF.
View Article and Find Full Text PDFArticle Synopsis
- * The impact of miR-155 on cardiovascular diseases is complicated; it can either promote or prevent conditions like atherosclerosis, indicating that more research is needed for a clearer understanding of its role.
- * Exosomal miRNAs, including miR-155, are crucial for cardiovascular health, affecting gene expression and are linked to multiple cardiovascular disorders such as heart failure and pulmonary hypertension.
Background: This study investigated the clinical outcomes at the minimum and maximum levels of hematocrit (HCT) during cardiopulmonary bypass (CPB) in low-risk patients undergoing coronary artery bypass graft (CABG) surgery.
Materials And Methods: In this cross-sectional study, 85 patients who underwent CABG with an ejection fraction of greater than 35% were selected. Based on the HCT range during CPB, patients were divided into two groups: minimum HCT: HCT = 16-18% and maximum HCT: HCT = 25-27%.
Background: Metformin is commonly prescribed to treat polycystic ovary syndrome (PCOS) patients, but in some cases, it may not be effective even at high doses or may cause intolerable side effects. Therefore, recent studies have examined the impact of combining metformin with other antidiabetic medications.
Methods: A systematic search was performed in Scopus, PubMed, Web of Science, and Embase up to 30 June 2023.
Heart failure (HF) is a pervasive clinical challenge characterized by compromised cardiac function and reduced quality of life. The kinin-kallikrein system (KSS), a multifaceted peptide cascade, has garnered substantial attention due to its potential role in HF. Through activation of B1 and/or B2 receptors and downstream signaling, kinins modulate various physiological processes, including inflammation, coagulation, pain, blood pressure control, and vascular permeability.
View Article and Find Full Text PDFBackground: The left ventricular dysfunction 36 (LVD-36) questionnaire is considered to be a tool to assess the impact of left ventricle impairment on patients' daily life. This methodological study was aimed to translate and assess the validity and reliability of the Persian draft of the LVD-36 questionnaire among Iranian heart failure (HF) patients.
Methods: We recruited stable HF patients who referred to an outpatient heart clinic in Isfahan, Iran.
Background: Inflammation has been suggested to play a role in heart failure (HF) pathogenesis. However, the role of platelet-to-lymphocyte ratio (PLR), as a novel biomarker, to assess HF prognosis needs to be investigated. We sought to evaluate the impact of PLR on HF clinical outcomes.
View Article and Find Full Text PDFPrognostic Implication of Preprocedural Pulmonary Hypertension in Patients with Severe Aortic Valve Stenosis Undergoing Transcatheter Aortic Valve Implantation: A Systematic Review and Meta-analysis.
Cardiol Rev
January 2024
Pulmonary hypertension (PH) is a common comorbidity in patients with aortic stenosis (AS) who are candidates for transcatheter aortic valve implantation (TAVI). Herein, we sought to elucidate the prognostic value of preprocedural PH on the early and late mortality after TAVI. The Cochrane Library, Scopus, PubMed, Web of Science, Embase, and ProQuest were screened using a predefined search query.
View Article and Find Full Text PDFLipid accumulation product and visceral adiposity index for incidence of cardiovascular diseases and mortality; results from 13 years follow-up in Isfahan cohort study.
Obes Sci Pract
February 2024
Background: /Aims: Visceral adiposity index (VAI) and lipid accumulation product (LAP) are novel anthropometric indices that have shown an association with metabolic syndrome; however, limited data are available regarding the predictive performance of these indices for the incidence of cardiovascular diseases (CVD) and mortality.
Methods: This study was performed on the data retrieved from Isfahan Cohort Study (ICS). ICS is an ongoing population-based cohort study conducted in 3 counties in central Iran.
The study of social cognition has extended across the lifespan with a recent special focus on the impacts of aging on the social-cognitive brain. This review summarizes current knowledge on social perception, theory of mind, empathy, and social behavior from a social-cognitive neuroscience of aging perspective and identifies new directions for studying the aging social-cognitive brain. These new directions highlight the need for (i) standardized operationalization and analysis of social-cognitive constructs; (ii) use of naturalistic paradigms to enhance ecological validity of social-cognitive measures; (iii) application of repeated assessments via single-N designs for robust delineation of social-cognitive processes in the aging brain; (iv) increased representation of vulnerable aging populations in social-cognitive brain research to enhance diversity, promote generalizability, and allow for cross-population comparisons.
View Article and Find Full Text PDFRheumatoid arthritis (RA) is an idiopathic, autoimmune connective tissue disorder that primarily affects the synovial joints, causing symmetric, erosive-deforming polyarthritis. It is also associated with extra-articular manifestations, particularly cardiovascular (CV) diseases (CVD). CV risk modification in RA remains unsolved despite recent advances in the management of RA.
View Article and Find Full Text PDFArticle Synopsis
- * A total of 37 studies (9 randomized controlled trials and 28 cohort studies) were reviewed, with the cohort studies showing a significant reduction in both systolic and diastolic blood pressure after treatment.
- * The blood pressure-lowering effect of levothyroxine is particularly notable in Caucasians and in SCH patients who start with higher thyroid-stimulating hormone (TSH) levels and have a significant reduction to normal levels.
Background: Neutrophil to lymphocyte ratio (NLR), as a recent inflammatory index, has been reported to be a prognostic tool in different diseases. However, implication of this ratio in heart failure (HF) is less investigated. In this systematic review and meta-analysis, we aimed to assess the potential impact of NLR on HF clinical outcomes.
View Article and Find Full Text PDFObjective: Inflammatory biomarkers are novel tools to assess the prognosis of different cardiovascular diseases. We evaluated the impact of the monocyte-to-lymphocyte ratio (MLR) on clinical outcomes in patients with coronary heart disease (CHD).
Methods: We systematically screened English-language articles in PubMed, Scopus, and Web of Science to 31 August 2022.