Treatment variables associated with outcome in emergency department patients with suspected sepsis.

Background: Early treatment is advocated in the management of patients with suspected sepsis in the emergency department (ED). We sought to understand the association between the ED treatments and outcome in patients admitted with suspected sepsis. The treatments studied were: (i) the time to antibiotics, where time zero is the time the patient was booked in which is also the triage time; (ii) the volume of intravenous fluid (IVF); (iii) mean arterial pressure (MAP) after 2000 ml of IVF and (iv) the final MAP in the ED.

The REDS score: a new scoring system to risk-stratify emergency department suspected sepsis: a derivation and validation study.

Objective: To derive and validate a new clinical prediction rule to risk-stratify emergency department (ED) patients admitted with suspected sepsis.

Design: Retrospective prognostic study of prospectively collected data.

Setting: ED.