Skeletal muscle relaxants as adjunctive pain control following cardiothoracic surgery: a systematic review protocol.

Introduction: Multimodal pain control following cardiothoracic surgery remains a focus in international guidelines. We hypothesise that non-depolarising skeletal muscle relaxants can prove to be a useful adjunct for this population.

Methods/analysis: This systematic review will focus on human adult studies of pain control using muscle relaxants within 1 week following cardiac and thoracic surgery available in PubMed, Cochrane Central, Web of Science and EMBASE.

The role of aspirin, statins, colchicine, and IL-1 inhibitors in prevention of cardiovascular events: a systematic integrative review.

Context: Cardiovascular disease (CVD) is the leading cause of death in the United States. As such, an unmet need exists in the primary and secondary prevention of adverse cardiovascular events (CVEs). Specifically, identifying drugs that can reduce the progression of CVD and serious adverse events is much needed.

Potential Therapeutic Treatments for Doxorubicin-Induced Cardiomyopathy.

Doxorubicin (DOX) is an anthracycline antibiotic used to treat many cancers, including breast cancer, leukemia, and Hodgkin's lymphoma. Positive aspects of DOX use are limited by the cardiomyopathy that it may cause. For this reason, it is crucial to uncover effective treatments against DOX-induced cardiomyopathy (DIC).