Linking cross-reactivity clusters of food and respiratory allergens in PAMD@ to asthma and duration of allergy.

Background: Component resolved diagnosis, recently redefined as precision allergy medicine diagnosis - PAMD@, may help understanding allergic cross-reactivity patterns among polysensitized patients and their clinical implication.

Objective: We aimed to investigate similarities among allergens by empirically determining the occurrence of co-sensitization patterns and to relate them to clinical features, in particular to asthma.

Methods: A retrospective cohort study in 1057 participants suspected to have allergic sensitization was performed in Vienna.