The Effect of Melatonin on Analgesia, Anxiety, and Intraocular Pressure (IOP) in Cataract Surgery Under Topical Anesthesia.

Purpose: This study investigated the effect of oral melatonin as a premedication before cataract surgery on pain score, anxiety, surgical conditions, and intraocular pressure (IOP) during cataract surgery with phacoemulsification under topical anesthesia.

Design: This randomized, double-blind prospective study was conducted among 120 patients aged 50 to 80.

Methods: Patients were randomly assigned to receive either sublingual melatonin 3 mg or placebo 60 min before surgery.

Comparing the Effects of Pregabalin and Clonidine on Postoperative Pain in Tonsillectomy: A Randomized, Double-Blind, Prospective Clinical Trial.

Background: Tonsillectomy is one of the most common surgical procedures. This study compared the effect of Pregabalin and Clonidine on postoperative pain in adult patients undergoing elective tonsillectomy.

Methods: This randomized, double-blind, prospective clinical trial was conducted among 92 patients aged 20 to 50.