Publications by authors named "Shabnam Khan"

Background: Pain around or behind the patella during activities like running, climbing stairs, jumping or squatting is termed as Patellofemoral pain syndrome (PFPS). The causes of PFPS are multifactorial. An improper gluteal muscle function may cause an increment in hip joint adduction and internal rotation movement during weight-bearing activities is one of the major causes of PFPS.

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The present work summarizes the fabrication of an amine-functionalized cadmium-based metal-organic framework (MOF), {[Cd(AT)(BP)]·4DMF} or , by adopting a simple solvothermal approach using 2-aminoterephthalic acid (AT) as the main linker, while 4,4'-bipyridyl (BP) as an auxiliary linker. The structure of was validated by the single-crystal X-ray diffraction technique that revealed the formation of an overall three-dimensional network with BP acting as a bridge between the 2D sheets of the MOF. The robust framework of decorated with a free amine functional group was utilized for energy storage application.

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Background: The pandemic exacerbated burnout experienced by healthcare personnel, whose mental health had long been a public health concern before COVID-19. This study used the Copenhagen burnout inventory (CBI) tool to assess burnout and identify predictors among Indian healthcare workers managing COVID-19.

Methods: A cross-sectional study was conducted from June to December 2022, after the third pandemic wave.

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Herein, metal-organic framework (MOF)-based adsorbents are designed with distinct hard and soft metal building units, namely, [CoCo(PD)(BP)] () and [CuCu(PD)(BP)] (), where HPD = pyrazine-1,4-diide-2,3-dicarboxylic acid and BP = 4,4'-bipyridine. The designed MOFs were characterized via spectral and SCXRD techniques, which confirm the mixed-valent states (+1 and +2) of the metal ions. Topological analysis revealed the rare and topologies for Co MOF, while Cu-MOF exhibits a unique topology in the 8-c net (point symbol for net: {4·6}).

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Nowadays, the fabrication of 2D metal-organic nanosheets (2D MONs) has entered the research arena fascinating researchers worldwide. However, a lack of efficient and facile methods has remained a bottleneck for the manufacturing of these 2D MONs. Herein, a 2D metal-organic framework (MOF), i.

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(1) Background: Staphylococcus aureus (S. aureus) is one of the most frequent causes of biofilm-associated infections. With the emergence of antibiotic-resistant, especially methicillin-resistant S.

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Objective: To investigate the mutation in Vangl1 gene in patients of myelomeningocele.

Methods: The cross-sectional study was conducted from July 2017 to December 2017 in the Dow Diagnostic and Research Laboratory, Karachi, after approval from the ethics review committee of Dow University of Health Sciences, Karachi, and comprised clinically diagnosed infants and 10 healthy individuals from the outpatient department of Jinnah Postgraduate Medical Centre, Karachi. Several anatomical parameters were considered, such as size and site of the cyst.

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Aim The correlation of subclinical hypothyroidism (SCH) and polycystic ovary syndrome (PCOS) is a still insufficiently explored entity. The aim of this study was to determine the correlation between SCH and PCOS along with the impact of SCH on metabolic and hormonal parameters in women with PCOS. Methodology This cross-sectional study was conducted at the Gynecology Outpatient Department of Ziauddin Hospital Kemari, Karachi, Pakistan, from June 2019 to December 2019.

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The present work reports the development of nanostructured material from Cashew nut shell liquid (CNSL, an agro byproduct of cashew industry, 87% cardanol) to evaluate their potential in antibacterial applications as a substitute of petroleum feedstock via an energy-efficient method. The nanostructured material was synthesized by coordination polymerization reaction of cardanol and divalent Mn(II) salt with the aid of microwave irradiations. FTIR spectroscopy was used to confirm the proposed structure of the synthesized materials.

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Amine terminated polyureas [ATPUa] were synthesized by 'in situ' condensation polymerization of toluene diisocyanate (TDI) with equimolar ratio of ethylene diamine (ED) and water. Incorporating the completely half-filled {Mn(II) d}, partially filled {Co(II) d, Ni(II) d} and fulfilled {Zn(II) d} divalent metal ions in APTUa generated the coordination polyureas (CPa). The structure and geometry of resulting CPa was ascertained by spectral techniques, the Fourier transform (FTIR), UV-Visible and nuclear magnetic resonance (H NMR) spectroscopy.

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Aim: Aim of the present study was to carry out the partial purification and biochemical characterization of glutathione S-transferase (GST) from the somatic tissue of ruminal amphistome parasite, (Gc) infecting Indian water buffalo ().

Materials And Methods: The crude somatic homogenate of Gc was subjected to progressive ammonium sulfate precipitation followed by size exclusion chromatography in a Sephacryl S 100-HR column. The partially purified GST was assayed spectrophotometrically, and the corresponding enzyme activity was also recorded in polyacrylamide gel.

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A series of novel coordination polyurethanes [HTPU-M, where M=Mn(II) 'd', Ni(II) 'd', and Zn(II) 'd'] have been synthesized to investigate the effect of divalent metal ions coordination on structure, thermal and adsorption properties of low molecular weight hydroxyl terminated polyurethane (HTPU). HTPU-M have been synthesized in situ where, OH group of HTPU (synthesized by the condensation polymerization reaction of ethylene glycol (EG) and toluene diisocyanate (TDI) in presence of catalyst) on condensation polymerization with metal acetate in presence of acid catalyst synthesized HTPU-M followed by coordination of metal ions with hetero atoms. The structure, composition and geometry of HTPU-M have been confirmed by vibrational spectrometry (FTIR), H NMR, elemental analysis and UV-Visible spectroscopy.

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Objective: To evaluate the fertility outcome in laparoscopic unilateral tubal reanastomosis.

Study Design: This was a retrospective observational study. The medical records of all patients who underwent laparoscopic unilateral tubal reanastomosis from October 2003 to October 2010 at the Center for Advanced Endoscopy and Infertility Treatment, Paul's Hospital, Cochin, Kerala, India, were analyzed.

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Background And Objectives: The purpose of this study is to estimate the cumulative incidence, patient characteristics, and potential risk factors for secondary hemorrhage after total laparoscopic hysterectomy.

Methods: All women who underwent total laparoscopic hysterectomy at Paul's Hospital between January 2004 and April 2012 were included in the study. Patients who had bleeding per vaginam between 24 hours and 6 weeks after primary surgery were included in the analysis.

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Article Synopsis
  • The study focuses on Withania somnifera (ashwagandha), which produces pharmacologically important compounds called withanolides, but lacks detailed insights into their biosynthesis across different growth stages.
  • Researchers collected two variants of the plant at five developmental stages and analyzed the levels of three key withanolides (withanolide-A, withanone, and withaferin A) in leaf and root tissues using high performance liquid chromatography.
  • They also examined the expression of five important biosynthetic genes, finding that withanolide levels were generally higher in leaves compared to roots, indicating potential differences in how these compounds are synthesized in various plant parts.
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Withania somnifera (ashwagandha) is a rich repository of large number of pharmacologically active secondary metabolites known as withanolides. Though the plant has been well characterized in terms of phytochemical profiles as well as pharmaceutical activities, but there is sparse information about the genes responsible for biosynthesis of these compounds. In this study, we have cloned and characterized a gene encoding squalene synthase (EC 2.

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