Delineating the mechanistic relevance of the gene and its mutational impact on gene expression and patients' survival in bladder cancer.

Bladder carcinoma (BLCA) is a widespread urological malignancy causing significant global mortality, often hindered by delayed diagnosis and limited treatments. BLCA frequently exhibits mutations, playing a pivotal role in its pathogenesis and underscoring the potential of targeting as a therapeutic approach for this prevalent urological malignancy. Tumor tissues from 50 bladder cancer patients were used for mutational analysis in 's mutation-rich exons (5, 7, & 8).