Publications by authors named "Shabda Gajbhiye"
Article Synopsis
- The phytopathogen studied has an ortholog of a surface layer protein (NpdA), but does not produce a traditional S-layer; the study aimed to confirm S-layer formation and its effects on virulence and other traits.
- Experimental confirmations showed that the pathogen AAC00-1 does form an NpdA-based S-layer but did not exhibit any significant differences in virulence compared to the mutant strain in watermelon fruit tests.
- NpdA orthologs were found in multiple strains of Betaproteobacteria and Gammaproteobacteria, suggesting that this new S-layer family plays a role in various Pseudomonadota, with potential implications for biofilm formation and material movement between cells.
Metabolic engineering strategies have been successfully implemented to improve the production of isobutanol, a next-generation biofuel, in . Here, we explore how two of these strategies, pathway re-localization and redox cofactor-balancing, affect the performance and physiology of isobutanol producing strains. We equipped yeast with isobutanol cassettes which had either a mitochondrial or cytosolic localized isobutanol pathway and used either a redox-imbalanced (NADPH-dependent) or redox-balanced (NADH-dependent) ketol-acid reductoisomerase enzyme.
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