Therapeutic effect of N, N-Diphenyl-1,4-phenylenediamine and adipose-derived stem cells coadministration on diabetic cardiomyopathy in type 1 diabetes mellitus-rat model.

Type 1 diabetes stem-cell-based treatment approach is among the leading therapeutic strategies for treating cardiac damage owing to the stem cells' regeneration capabilities. Mesenchymal stem cells derived from adipose tissue (AD-MSCs) have shown great potential in treating diabetic cardiomyopathy (DCM). Herein, we explored the antioxidant-supporting role of N, N'-diphenyl-1,4-phenylenediamine (DPPD) in enhancing the MSCs' therapeutic role in alleviating DCM complications in heart tissues of type 1 diabetic rats.

Amygdalin-folic acid-nanoparticles inhibit the proliferation of breast cancer and enhance the effect of radiotherapy through the modulation of tumor-promoting factors/ immunosuppressive modulators in vitro.

Introduction: Breast cancer (BC) cells often develop multiple mechanisms of chemo- and radio-resistance during tumor progression, which is the major reason for the failure of breast cancer therapy. Targeted nanomedicines have tremendous therapeutic potential in BC treatment over their free drug counterparts. Searching for chemo- and radio-sensitizers to overcome such resistance is therefore urgently required.

AD-MSCs and BM-MSCs Ameliorating Effects on The Metabolic and Hepato-renal Abnormalities in Type 1 Diabetic Rats.

Diabetes mellitus (DM) is one of the most serious threats in the 21th century throughout the human population that needs to be addressed cautiously. Nowadays, stem cell injection is considered among the most promising protocols for DM therapy; owing to its marked tissues and organs repair capability. Therefore, our 4 weeks study was undertaken to elucidate the probable beneficial effects of two types of adult mesenchymal stem cells (MSCs) on metabolism disturbance and some tissue function defects in diabetic rats.

Biochemical composition and antioxidant activities of Arthrospira (Spirulina) platensis in response to gamma irradiation.

Arthrospira (Spirulina) platensis is a blue-green alga, rich with bioactive components and nutrients. To evaluate effect of gamma irradiation, A. platensis was exposed to different doses of 0.

Radioactivity in the groundwater of a high background radiation area.

Natural radioactivity was measured in groundwater samples collected from 37 wells scattered in an inhabited area of high natural background radiation, in a purpose of radiation protection. The study area is adjacent to Aja heights of granitic composition in Hail province, Saudi Arabia. Initial screening for gross α and gross β activities showed levels exceeded the national regulation limits set out for gross α and gross β activities in drinking water.

Production and significance of CCAAT enhancer binding proteins alpha and beta in sinonasal inverted papilloma.

Sinonasal inverted papilloma (SIP) is a rare benign tumor featuring increased cell proliferation, a tendency toward squamous differentiation, recurrence and malignant transformation. The CCAAT enhancer binding proteins, C/EBPs, are transcription factors regulating the proliferation and differentiation of various types of cells, including epithelial cells. We prospectively investigated the production of these transcription factors and the related proliferation and differentiation targets, keratin-10, keratin-15 and cyclin-D1, in 26 SIP patients and 8 sinonasal polyposis cases suspected for SIP.

Assessment of the global fallout of plutonium isotopes and americium-241 in the soil of the central region of Saudi Arabia.

A radiochemical technique for determination of plutonium isotopes and 241Am in soil samples is tested against IAEA-standard reference materials to determine its accuracy and precision for reliable results. The technique is then used in the investigation of topsoil samples, collected from the natural environment of the central region of Saudi Arabia, to assess the effect of fallout accumulation of these radionuclides in the region. Plutonium and americium were sequentially separated from all other components of the sample by anion-exchange chromatography and co-precipitated with Nd3+ as fluorides.

Differential effects of thiobencarb toxicity on growth and photosynthesis of Anabaena variabilis with changes in phosphate level.

A thiobencarb dose of 3 mg L(-1) reduced the protein content of Anabaena variabilis, whereas it elevated the carbohydrate content. Measurements of Anabaena growth, photosynthetic activity, and respiration rate revealed that the high dose of phosphate (0.53 mM) exerted no additional toxic effect to thiobencarb toxicity.

Effect of pendimethalin on growth and photosynthetic activity of Protosiphon botryoides in different nutrient states.

The effect of pendimethalin on the green alga Protosiphon botryoides was investigated. Results indicate that specific growth rate, cell number, chlorophyll a level, and dry weight yield significantly decrease with increasing pendimethalin concentrations, while protein and carbohydrate contents increase significantly. On the other hand, photosynthetic activity decreases whereas dark respiration increases with high pendimethalin concentrations.

Chlorophyll a fluorescence and photosynthetic activity as tools for the evaluation of simazine toxicity to Protosiphon botryoides and Anabaena variabilis.

On studying the effect of simazine on Protosiphon botryoides and Anabaena variabilis, data revealed that chlorophyll a content and dry weight were decreased with the increase in simazine concentration. High concentration of simazine (0.8 mg L(-1)) reduced gross photosynthesis and carbohydrate content, whereas protein content and respiration rate were increased.

Evaluation of the contribution of smoking to total blood polonium-210 in Saudi population.

A preliminary study of 210Po concentrations in the blood of some smokers and nonsmokers is presented in order to evaluate the contribution of smoking to total blood 210Po in Saudi population. Blood samples were collected from 30 volunteers and analyzed by high resolution alpha-spectrometry using a radiochemical technique. The technique is based on the separation of polonium from other components of the sample by wet ashing with an HNO3/H2O2 oxidizing mixture and spontaneous deposition on a silver disc under the relevant conditions for alpha-particle counting.

Ion exchange behaviour of hydrous tin oxide: Kinetics of anion exchange.

The kinetic behaviour of Cl(-), Br(-) and SCN(-) exchanges on hydrous tin oxide have been investigated under conditions of particle diffusion and the limited bath technique. Values for the diffusion coefficients, energy of activation and entropy of activation have been calculated. The data obtained have been compared with those reported for other organic and inorganic exchangers.

Studies on extraction of indium by tributyl phosphate from thiocyanate solutions.

Indium can be quantitatively separated from a large number of elements which are usually associated with it, by extraction with 15% tributyl phosphate solution in kerosene from hydrochloric acid (pH 1)/0.5M potassium thiocyanate medium and stripping with 6M nitric acid. The equilibration takes 20 min.

Studies on extraction of thorium from nitrate solutions with quaternary ammonium halides.

Thorium can be quantitatively extracted with 0.1 M Hyamine 1622 in dichloroethane from 0.25M nitric acid/2M sodium nitrate and stripped from the organic phase with 0.