Publications by authors named "Sha-Sha Jia"
The Aux/IAA family proteins, key components of the auxin signaling pathway, are plant-specific transcription factors with important roles in regulating a wide range of plant growth and developmental events. The family genes have been extensively studied in Arabidopsis. However, most of the family genes in rice have not been functionally studied.
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- * The patient exhibited difficulties in speech, including single-word retrieval and repetition issues, along with notable brain atrophy in the left parietal cortex.
- * Genetic testing revealed a specific 10-bp deletion mutation in the granulin gene, causing significant changes in the protein structure, and identified a new mutation site linked to a rare form of logopenic variant PPA (lvPPA).
Serum Uric Acid Levels in Neurodegenerative Disorders: A Cross-Sectional Study.
J Alzheimers Dis
November 2022
Background: Excessive oxidative stress may contribute to neurodegeneration by leading to protein aggregation and mitochondrial dysfunction. Uric acid (UA) is an important endogenous antioxidant that protects against oxidative stress, yet its exact role in neurodegeneration remains unclear.
Objective: To explore the performance of serum UA in neurodegenerative disorders.
Background: We conducted a meta-analysis to evaluates the incidence of the gastrointestinal (GI) adverse events with the use of PD-1 inhibitors among patients with advanced non-small cell lung cancer (NSCLC).
Methods: The PICOs (participants, intervention, comparison, and outcomes) elements were used for the selection of studies to meet the inclusion and exclusion criteria. Google Scholar, PubMed, Science Direct and proceedings of major oncology conferences were systematically searched from their inception to December 2020, to identify studies which reported the GI adverse events of PD-1 inhibitors among patients with NSCLC.
This study evaluates the impact of the use of antibiotics on the effectiveness of nivolumab in the treatment of advanced/metastatic non-small cell lung cancer (NSCLC). A literature search was conducted in various electronic databases to identify studies, which evaluated the impact of antibiotic use on the survival of patients with advanced/metastatic NSCLC who have been treated with nivolumab. Six studies, comprising a total of 787 patients with 37.
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- The study aimed to determine whether a specific genetic variation in the alpha(2B)-adrenergic receptor gene is linked to migraine susceptibility in a Chinese Han population.
- A case-control approach involved comparing 368 migraine patients with 517 healthy controls, using DNA analysis to investigate the polymorphism.
- The results indicated no significant association between the genetic variation and migraine risk, suggesting the polymorphism may not play a functional role in this condition.