Antimycobacterial activity of luteolin in resistant Mycobacterium tuberculosis isolates and cytotoxicity on L929 cells.

Mycobacterium tuberculosis (M. tuberculosis) bacteria can cause oxidative stress and the production of inflammatory cytokines, creating an environment that enhances tumour formation, progression and metastasis. Epidemiological studies have found a link between lung cancer and tuberculosis (TB), but the cellular mechanism is still unclear.

Psychiatric Disorders and Associated Factors in Left Ventricular Assist Device Implantation and Heart Transplant Candidates.

Introduction: End-stage heart failure (ESHF) remains a significant challenge despite optimal treatment, with heart transplantation (HTx) being the gold standard of care. Mechanical circulatory support (MCS) devices such as left ventricular assist devices (LVADs) are increasingly used for temporary or permanent treatment. Psychiatric comorbidities are common in patients with ESHF and may affect treatment outcomes, but the relationship between sociodemographic, clinical, and psychiatric characteristics remains unclear.

Potential impact of obstetric history on postmenopausal fragility fracture risk: A reassessment of the Fracture Risk Assessment Tool.

Objectives: This study aimed to evaluate the impact of integrating obstetric parameters into the Fracture Risk Assessment Tool (FRAX) on the precision of risk assessment.

Patients And Methods: In this retrospective study, patients who experienced postmenopausal fragility fractures of the distal radius, proximal femur, or lumbar vertebrae between January 1, 2021, and December 31, 2023, were included. Obstetric histories, along with standard FRAX parameters, were obtained by phone interviews.

Evaluation of Candidemia in Solid-Organ Transplant Recipients.

Objectives: Solid-organ transplant recipients have high rates of invasive fungal infections. Candida species are the most commonly isolated fungi. Our aim was to identify risk factors, clinical presentations, and outcomes of candidemia in solid-organ transplant recipients.

Determination of Risk Factors for Acute Kidney Injury In Orthotopic Cardiac Transplantation.

Background: In this study, we try to determine risk factors for acute kidney injury in orthotopic cardiac transplantation patients.

Methods: Between February 2003 and December 2022, all cardiac transplantation patients were retrospectively reviewed. Finally, 102 patients enrolled in this study.

Herpes Zoster Infections in Solid-Organ Transplant Recipients.

Objectives: Herpes zoster infections can be complicated and mortal in solid-organ transplant recipients. In our study, we investigated herpes zoster infections in solid-organ transplant recipients.

Materials And Methods: UntilJune 2022, our center has performed 3342 kidney, 708 liver, and 148 heart transplants.

Tactile Perception of Coated Smooth Surfaces.

Although surface coating is commonly utilized in many industries for improving the aesthetics and functionality of the end product, our tactile perception of coated surfaces has not been investigated in depth yet. In fact, there are only a few studies investigating the effect of coating material on our tactile perception of extremely smooth surfaces having roughness amplitudes in the order of a few nanometers. Moreover, the current literature needs more studies linking the physical measurements performed on these surfaces to our tactile perception in order to further understand the adhesive contact mechanism leading to our percept.

Effects of litter size and caging on physical and mental development in rats.

As a multidisciplinary field, laboratory animal science promotes or accelerates the emergence of innovative ideas and products. As research has increased, so has the demand for laboratory animals with reliable, standardized characteristics. Thus, the breeding, reproduction, and welfare of laboratory animals are now animals reliable and more.

Robust Transceiver Design for IRS-Assisted Cascaded MIMO Communication Systems.

Intelligent reconfigurable surfaces (IRSs) have gained much attention due to their passive behavior that can be a successor to relays in many applications. However, traditional relay systems might still be a perfect choice when reliability and throughput are the main concerns in a communication system. In this work, we use an IRS along with a decode-and-forward relay to provide a possible solution to address one of the main challenges of future wireless networks which is providing reliability.

Preliminary Report of the Academic CAR-T (ISIKOK-19) Cell Clinical Trial in Turkey: Characterization of Product and Outcomes of Clinical Application.

Objective: Chimeric antigen receptor T (CAR-T) cell therapies have already made an impact on the treatment of B-cell malignancies. Although CAR-T cell therapies are promising, there are concerns about commercial products regarding their affordability and sustainability. In this preliminary study, the results of the first production and clinical data of an academic CAR-T cell (ISIKOK-19) trial in Turkey are presented.

Splenectomy in İmmune Thrombocytopenia: A Retrospective Analysis of 25-Year Follow-up Data from a Tertiary Health Clinic.

Immune thrombocytopenia (ITP) is a rare autoimmune disorder presenting with isolated thrombocytopenia. Splenectomy is still one of the treatment alternatives for these patients. Here we aim to analyze long term follow-up data of splenectomy in immune thrombocytopenia.

Approach to optimal assessment of right ventricular remodelling in heart transplant recipients: insights from myocardial work index, T1 mapping, and endomyocardial biopsy.

Aims: Right ventricular (RV) dysfunction is an important cause of graft failure after heart transplantation (HTx). We sought to investigate relative merits of echocardiographic tools and cardiac magnetic resonance (CMR) with T1 mapping for the assessment of functional adaptation and remodelling of the RV in HTx recipients.

Methods And Results: Sixty-one complete data set of echocardiography, CMR, right heart catheterization, and biopsy were obtained.

Deep Unfolding of Iteratively Reweighted ADMM for Wireless RF Sensing.

We address the detection of material defects, which are inside a layered material structure using compressive sensing-based multiple-input and multiple-output (MIMO) wireless radar. Here, strong clutter due to the reflection of the layered structure's surface often makes the detection of the defects challenging. Thus, sophisticated signal separation methods are required for improved defect detection.

Determination of Cytokine Gene Polymorphisms in a Heart Transplant Patient Resistant to Desensitization Therapy: Case Report.

Heart transplant is the best treatment option for end-stage heart failure. The major goals in solid-organ transplant are organ survivability and functionality. The effects of anti-HLA antibodies and cytokines are important for immune response.

A Case Report of Ventricular Fibrillation Survival by Left Ventricular Assist Device for Hours.

In recent years, the population of patients implanted with a left ventricular assist device has been increasing. Ventricular arrhythmias are the most interesting and most deadly complications among patients with these implants. Ventricular arrhythmias may cause cardiovascular collapse and death in some cases, whereas they may be asymptomatic or less symptomatic in others.

Clutter Suppression for Indoor Self-Localization Systems by Iteratively Reweighted Low-Rank Plus Sparse Recovery.

Self-localization based on passive RFID-based has many potential applications. One of the main challenges it faces is the suppression of the reflected signals from unwanted objects (i.e.

Direct aortic transcatheter aortic valve implantation.

Transcatheter aortic valve implantation (TAVI) is a safe and effective alternative to surgical valve replacement in intermediate and even in low-risk patient cohorts. Direct aortic (DAo) route may be used in patients with severe peripheral vascular disease. Here, we present an 88-year old patient hospitalized with cardiogenic shock.

Location-Privacy Leakage and Integrated Solutions for 5G Cellular Networks and Beyond.

The fifth generation (5G) of cellular networks improves the precision of user localization and provides the means to disclose location information to over-the-top (OTT) service providers. The network data analytics function (NWDAF) can further elaborate this information at an aggregated level using artificial intelligence techniques. These powerful features may lead to the improper use of user location information by mobile network operators (MNOs) and OTT service providers.

Neurologic Complications After Pediatric Heart Transplant: A Single-Center Experience.

Objectives: Neurologic complications that can lead to serious mortality and morbidity in pediatric heart transplant recipients have been reported to range from 23.6% to 45%. In this study, the frequency, time, cause, and characteristics of neurologic complications in pediatric heart transplant recipients were evaluated.

Longitudinal Strain and Strain Rate for Estimating Left Ventricular Filling Pressure in Heart Transplant Recipients.

Traditional parameters have limited value to estimate left ventricular filling pressure (LVFP) in orthotropic heart transplant (OHT) recipients. We hypothesized that global longitudinal strain (GLS), diastolic, and systolic strain rate (SR) would be depressed in OHT recipients with elevated LVFP and could overcome the limitations of traditional parameters. We studied consecutively OHT patients at the time of endomyocardial biopsies and retrospectively pretransplantation studies conforming to the same protocol.

Preclinical Assessment of Efficacy and Safety Analysis of CAR-T Cells (ISIKOK-19) Targeting CD19-Expressing B-Cells for the First Turkish Academic Clinical Trial with Relapsed/Refractory ALL and NHL Patients.

Objective: Relapsed and refractory CD19-positive B-cell acute lymphoblastic leukemia (ALL) and non-Hodgkin lymphoma (NHL) are the focus of studies on hematological cancers. Treatment of these malignancies has undergone recent transformation with the development of new gene therapy and molecular biology techniques, which are safer and well-tolerated therapeutic approaches. The CD19 antigen is the most studied therapeutic target in these hematological cancers.

Management of pediatric cardiac transplantation candidates with pulmonary hypertension and high pulmonary vascular resistance.

Background And Objectives: Right ventricular failure is an important cause of mortality and morbidity after orthotopic heart transplantation (OHT). The right ventricle of the donor may fail to accommodate to the high pulmonary vascular resistance (PVR) of the recipient. Pulmonary hypertension (PH) due to chronic heart failure with PVRi > 4 Wood units.