A bibliometric analysis: what do we know about edible coatings?

Unlabelled: Packaging aims first to protect the quality and safety of food. Although synthetic packaging is easy and practical to use, it significantly poses many health and environmental hazards. In this context, the need for environmentally and food-friendly packaging is increasing.

The role of ceranib-2 and its nanoform on the decrease of telomerase levels in human non-small cell cancer.

Background: Ceranib-2, an acid ceramidase (AC) inhibitor, can inhibit cancer cell proliferation and tumor development. However, poor water solubility and low cellular bioavailability limit its efficacy in cancer treatment.

Methods And Results: This study aimed to investigate the cell death induced by ceranib-2 and its solid lipid nanoformulation (ceranib-2-SLN) produced by the hot homogenization technique and the synergistic relationship between ceramide and telomerase in vitro and in silico.

Exogenous Ceramide Treatment Induce Death and Cytotoxicity in Glioma Cells.

Aim: To evaluate the cytotoxic and proapoptotic effects of C6 ceramide on the C6 rat glioma cell line.

Material And Methods: The C6 rat glioma cell line was evaluated. Using a confocal microscope and the appropriate software, the cytotoxic effects of C6 ceramide were identified using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-2H tetrazolium bromide (MTT) colorimetric experiments.

Beyond expectations: safinamide's unprecedented neuroprotective impact on acute spinal cord injury.

Background: Traumatic spinal cord injury (SCI) is the most common preventable cause of morbidity. Despite rapid advances in medicine, effective pharmacological treatment against SCI has not yet been confirmed. This study aimed to investigate the possible anti-inflammatory, antiapoptotic, and neuroprotective effects of safinamide after SCI in a rat model.

In vivo study of the utility of selective intra-arterial injection of thiopental for neuroprotection in reversible cerebral ischemia.

Background: Neuroprotective agents are needed to reduce cerebral damage during surgical or neurointerventional procedures including stroke patients.

Purpose: To evaluate if thiopental can be used as a neuroprotective agent when injected intra-arterially in a transient ischemia model.

Material And Methods: In total, 24 rabbits were studied as four groups of six animals.

The Effect of Reiki and Aromatherapy on Vital Signs, Oxygen Saturation, and Anxiety Level in Patients Undergoing Upper Gastrointestinal Endoscopy: A Randomized Controlled Study.

This randomized controlled study aimed to determine the effect of Reiki and aromatherapy on vital signs, oxygen saturation, and anxiety level in patients undergoing upper gastrointestinal endoscopy. The sample consisted of 100 patients divided into Reiki (n = 34), aromatherapy (n = 33), and control (n = 33) groups. Data were collected 3 times (before, during, and after the procedure) using a descriptive characteristics questionnaire, a follow-up form, and the State Anxiety Subscale.

Alternations in interleukin-1β and nuclear factor kappa beta activity (NF-kB) in rat liver due to the co-exposure of Cadmium and Arsenic: Protective role of curcumin.

Cadmium chloride (Cd) and sodium arsenite (As) are two prominent examples of non-biodegradable substances that accumulate in ecosystems, pose a serious risk to human health and are not biodegradable. Although the toxicity caused by individual use of Cd and As is known, the toxicity of combined use (Cd+As) to mammals is poorly understood. The present study aims to investigate the hepatoprotective effect of curcumin (CUR), a naturally occurring bioactive component isolated from the root stem of Curcuma longa Linn.

Unilateral Dynamic Stabilization in Recurrent Lumbar Disc Herniation.

Aim: To evaluate the effectiveness and outcomes of unilateral dynamic stabilization in patients with recurrent lumbar disc herniation (RLDH).

Material And Methods: Patients requiring an operation due to RLDH at the L4?5 level were included in the study.They divided into the following two groups: SD group who had only revision discectomy (n=20) and DD group who had unilateral dynamic rod stabilization with discectomy (n=20).

Investigation of the Efficiency of Psychological Support Videos as an Approach to the Protection of Mental Health of Medics During the Pandemic Process.

Background: The aim of this study is to evaluate whether providing psychological support to healthcare professionals who are actively involved in the pandemic process will reduce the psychological risk factors created by the pandemic on healthcare professionals.

Methods: A total of 440 healthcare professionals working in different positions in 2 state hospitals, which are considered pandemic hospitals, were included in the study. Sociodemographic Data Form, Hospital Anxiety and Depression Inventory, and Psychological Resilience Scale were used in the study, which was carried out with the experimental design pre-test-post-test model before the experiment.

Neuroprotective Effects of Milrinone on Acute Traumatic Brain Injury.

Background: Traumatic brain injury is still an important health problem worldwide. Traumatic brain injury not only causes direct mechanical damage to the brain but also induces biochemical changes that lead to secondary nerve cell loss. In this study, we investigated the neuroprotective effect of milrinone after traumatic brain injury (TBI) in a rat model.

Antitumor Effects of Turmeric on OVCAR-3 Ovarian Cancer Cell Lines.

Introduction: Ovarian cancer is the deadliest gynecological malignancy, usually not detected until the late stages. In vitro cell culture is a method used to study the behavior of cells in a controlled environment. Turmeric has attracted the attention of scientists due to its anticancer potential.

Antitumor Effects of L-citrulline on Hela Cervical Cancer Cell Lines.

Aim: Cervical cancer is the deadliest gynecological malignancy. This study aims to examine the anticancer effects of L-citrulline on HeLa cell culture.

Materials And Methods: HeLa cells were cultured in complete Eagle's minimum essential medium.

Pedicle Screw Fixation with Percutaneous Vertebroplasty for Traumatic Thoracolumbar Vertebral Compression Fracture.

Objective: This study aims to evaluate the clinical efficacy of percutaneous pedicle screw fixation (PPSF) combined with percutaneous vertebroplasty (PVP) for the treatment of the thoracolumbar vertebral compression fracture (VCF) without neurologic deficits.

Materials And Methods: This was a prospective observational study. Between January 2015 and December 2018, 62 patients who had suffered from traumatic thoracolumbar (VCF) burst fractures without neurologic deficits were included in this study.

The mediating role of patient satisfaction in the effect of patient visit experiences on word-of-mouth intention.

The purpose of this study is to find out whether patient experiences of examinations affect their word-of-mouth (WOM) intention and to identify the role of patient satisfaction with the physician in this effect. Data were collected via survey form ( = 1,100). Descriptive statistical methods, reliability analysis, exploratory factor analysis, confirmatory factor analysis, and structural equation modeling were used in the data analysis.

Cytotoxic Impact of N-Oleoylethanolamine on Bone Cancer Cells.

Background: Cancer is a complex disease that derives from the uncontrolled proliferation of cells. Bone cancer is a type of prevalent cancer that occurs both in young and adults. Bone cancer is most common in the long bones of the pelvis, arms and legs.

Spontaneous migration of a bullet in the cerebrum.

Herein, we report the case of a 32-year-old man who experienced spontaneous migration of a bullet within the brain following a gunshot injury. Emergent computed tomography revealed the bullet located in the posterosuperior side of mesencephalon. During follow-up after 10 days, the neurological status of the patient had worsened.

FOXA1 is associated with high tumor grade, myometrial invasion and lymph node invasion in endometrial endometrioid carcinoma.

Objectives: FOXA1 expression has been demonstrated in several hormone-dependent cancers. However, data are limited concerning the role of FOXA1 in endometrial cancers. The present study aimed to investigate FOXA1 expression via the microarray technique in benign hyperplasia, endometrial intraepithelial neoplasia, and endometrial endometrioid carcinoma.

The extent of cyclin D1 expression in endometrial pathologies and relevance of cyclin D1 with the clinicopathological features of endometrioid endometrial carcinoma.

Background: Cyclin D1, a member of the cyclin protein family, is instrumental in the cell cycle due to its influence on the progression from G1 to the S phase. Its overexpression causes reduced doubling time and is also associated with clonogenic growth. The purpose of the present study was to assess cyclin D1 expression in patients with simple hyperplasia (SH), endometrial intraepithelial neoplasia (EIN) and endometrioid endometrial carcinoma, and to evaluate whether there was an association between cyclin D1 expression and the clinicopathological features of endometrioid endometrial carcinoma.

The risk of malignancy according to Milan reporting system of salivary gland fine-needle aspiration with Becton Dickinson SurePath liquid-based processing.

Background: Fine-needle aspiration cytology (FNAC) is a noninvasive, safe, cost-effective, diagnostic procedure for the evaluation of salivary gland lesions and the selection of patients for surgery. The aim of this study was to analyze the risk of malignancy (ROM) according to the Milan reporting system of salivary gland FNA specimens using a liquid-based cytology (LBC) technique.

Methods: The cytological diagnosis of 459 cases between 2014 and 2017 was revised according to the Milan reporting system.

The diagnostic significance of trophoblast cell-surface antigen-2 expression in benign and malignant thyroid lesions.

Context: Thyroid cancers are the most common malignancy of the endocrine system. Over-expression of trophoblast cell-surface antigen 2 (TROP-2) in various tumors has been found to correlate with poor prognosis and aggressive tumor behavior.

Aims: The aim of this study was to evaluateTROP-2 expression in thyroid neoplasms.

HMGB1 expression in urothelial carcinoma of the bladder.

Purpose: HMGB1, the most important member of the high mobility group box protein family, is a nuclear protein with different functions in the cell; it has a role in cancer progression, angiogenesis, invasion, and metastasis development. We studied the expression of HMGB1 and whether it is a prognostic factor in urothelial carcinoma of bladder (UCB) or not.

Methods: The study included 90 cases that were histopathologically diagnosed with UCB in the tissue samples obtained by transurethral resection (TUR).

Effect of a new cross-linked hyaluronan gel on the staple line after sleeve gastrectomy in a rat model.

Purpose: To evaluate the effect of a new cross-linked hyaluronan (NCHA) gel on healing of the staple line in an experimental sleeve gastrectomy.

Methods: Eighteen rats were randomly divided into three groups. The control group (n = 6) received no medication.