Quantitative proteomic analysis to determine differentially expressed proteins in axenic amastigotes of Leishmania tropica and Leishmania major.

Cutaneous leishmaniasis is commonly caused by Leishmania major and Leishmania tropica. In the present study, the differential expression of proteins was identified in the amastigote-like forms of L. tropica and L.

Comparative Two-dimensional Gel Electrophoresis Maps for Amastigote-like Proteomes of Iranian and Isolates.

Background: and are the main causative agents of cutaneous leishmaniasis. Proteomics as a novel approaches could be used to evaluate protein expression levels in different stages of species. We compare the protein contents of amastigote-like forms in and using two-dimensional gel electrophoresis (2-DE) and bioinformatics methods.

Ferredoxin Gene Mutation in Iranian Trichomonas vaginalis Isolates.

Background: Trichomonas vaginalis causes trichomoniasis and metronidazole is its chosen drug for treatment. Ferredoxin has role in electron transport and carbohydrate metabolism and the conversion of an inactive form of metronidazole (CO) to its active form (CPR). Ferredoxin gene mutations reduce gene expression and increase its resistance to metronidazole.