Publications by authors named "Seyyed Soheil Aghaei"

This study intends to biosynthesize gold nanoparticles (AuNPs) using sp. KMN and to investigate its potential antibiofilm, cytotoxic and antioxidant activities. The physicochemical characterization of biosynthesize AuNPs was identified by UV-Visible, energy-dispersive X-ray, and Fourier transform infrared spectroscopy, as well as high-resolution transmission electron microscopy, X-ray diffraction, zeta potential, and dynamic light scattering methods.

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In this research, we have investigated a novel magnetic nanocomposite including NiFeO@MIL-101(Fe)/GO for the delivery of the antibiotic tetracycline (TC). Moreover, the antibacterial activity of NiFeO@MIL-101(Fe)/GO, NiFeO@MIL-101(Fe)/GO/TC and pure TC was evaluated by agar well diffusion and minimum inhibitory concentration (MIC) methods on both Gram-negative () and Gram-positive () bacteria. In addition, the cytotoxicity of NiFeO@MIL-101(Fe)/GO/TC on HeLa cells was determined by an MTT assay which showed good results.

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Aims: The use of cyanobacterial cell extracts for the synthesis of zinc oxide nanoparticles (ZnO NPs) seems to be superior to other methods of synthesis because of its a green, environmentally friendly and low-cost approach. In this study, the cell extract of a newly characterized cyanobacterial strain Desertifilum sp. EAZ03 was used for the biosynthesis of ZnO NPs.

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Article Synopsis
  • Cyanobacteria are a promising source of bioactive compounds, and this study focused on synthesizing ZnO nanoparticles (CEN-ZnO NPs) using extracts from a specific cyanobacterium.
  • The synthesized nanoparticles, characterized by various techniques, showed effective antibacterial properties by inhibiting bacterial growth and disrupting biofilm formation, with minimal cytotoxic effects on healthy lung cells compared to cancer cells.
  • Flow cytometry results indicated that higher concentrations of CEN-ZnO NPs significantly reduced bacterial viability, suggesting potential applications in antimicrobial treatments.
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