Computed Tomography Scan and Clinical-based Complete Response Prediction in Locally Advanced Rectal Cancer after Neoadjuvant Chemoradiotherapy: A Machine Learning Approach.

Background: Treatment of locally advanced rectal cancer (LARC) involves neoadjuvant chemoradiotherapy (nCRT), followed by total mesorectal excision. Examining the response to treatment is one of the most important factors in the follow-up of patients; therefore, in this study, radiomics patterns derived from pretreatment computed tomography images in rectal cancer and its relationship with treatment response measurement criteria have been investigated.

Methods: Fifty patients with rectal adenocarcinoma who were candidates for nCRT and surgery were included.

Normal reference values for Tc-99m pertechnetate thyroid uptake in northern Iranian population: A single-center experience.

Background: The normal reference values for the thyroid uptake of radioactive iodine and Tc-99m pertechnetate in euthyroid patients vary by geographical location as well as the amount of iodine intake in the diet. The present study examines the normal reference values for thyroid uptake of Tc-99m pertechnetate in the North of Iran.

Methods: The participants of this study were 64 patients (all over 20 years of age) who had referred to the Nuclear Medicine Center of the Shahid Beheshti Hospital for thyroid scan over the period between March 2018 and May 2020.

Pediatric effective dose assessment for routine computed tomography examinations in Tehran, Iran.

Background: The purpose of this study is to evaluate the effective dose (ED) for computed tomography (CT) examination in different age groups and medical exposure in pediatric imaging centers in Tehran, Iran.

Methods: Imaging data were collected from 532 pediatric patients from four age groups subjected to three prevalent procedures. National Cancer Institute CT (NCICT) software was used to calculate the ED value.

Evaluating the Radiosensitization Effect of Hydroxyapatite Nanoparticles on Human Breast Adenocarcinoma Cell Line and Fibroblast.

Background: Nanohydroxyapatite (nHAP) exhibit anti-proliferative effects on various cancer cells. However, to date, there are only a few studies on the radiosensitization effect of nHAP. The present study aimed to investigate the possible enhancement of the radiosensitization effect of nHAP on human breast adenocarcinoma cancer (MCF-7) and fibroblast.

The evaluation of radio-sensitivity of mung bean proteins aqueous extract on MCF-7, hela and fibroblast cell line.

Purpose: Breast cancer is one of the most common malignant tumors in women all over the world. Many of these women resist the common treatments. Therefore, it is important to find new products to increase the efficacy of the treatment process.

Development of Sm-DTPA-SPION as a theranostic dual contrast agents in SPECT/MRI.

Objectives: This study describes the preparation, biodistribution of Sm-DTPA-SPION after intravenous injection in rats.

Materials And Methods: The chelator DTPA dianhydride was conjugated to SPION using a small modification of the well-known cyclic anhydride method. Conjugation was done at a 1: 4 (SPION:ccDTPA) molar ratio.