Expression Profiling of (L) Superfamily of Genes in Various Human Eye Tissues.

Background: A disintegrin and metalloproteinase with thrombospondin motifs (ADAMTS) is a superfamily of extracellular proteinases found in both mammals and invertebrates. Although there is some evidence about the role of ADAMTSs in ocular diseases such as glaucoma and ectopia lentis, but there is little information about the expression patterns of and ADAMTS-like ( and ) genes in human ocular tissues. This study aimed to evaluate the expression profiling of (L) superfamily of genes in different ocular tissues based on age.