Anal Chem
December 2022
We report the development of a label-, antibody-, enzyme-, and amplification-free ratiometric fluorescent biosensor for low-cost and rapid (less than 12 min) diagnosis of COVID-19 from isolated RNA samples. The biosensor is designed on the basis of cytosine-modified antisense oligonucleotides specific for either N gene or RdRP gene that can form silver nanoclusters (AgNCs) with both green and red emission on an oligonucleotide via a one-step synthesis process. The presence of the target RNA sequence of SARS-CoV-2 causes a dual-emission ratiometric signal transduction, resulting in a limit of detection of 0.
View Article and Find Full Text PDFIn this paper, we developed a sequential chemical etching and selenization processes to synthesize Co-MoSex double-shelled hollow nanocages (CMS-DSHNCs) as high performance electrode materials for supercapacitor applications. Co-MoO yolk-shelled hollow nanocages were firstly synthesized using a solvothermal process through facile ion-exchange reactions between zeolitic imidazolate framework-67 (ZIF-67) and MoO ions. By applying a solvothermal temperature of 160 °C in the presence of SeO and subsequently annealing strategy, CMS-DSHNCs were successfully synthesized with a yolk-shell hierarchically hollow and porous morphology of mixed metal selenides.
View Article and Find Full Text PDFACS Appl Mater Interfaces
August 2020
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
View Article and Find Full Text PDFElectrochemical sensors are the tools to detect the accurate and sensitive miRs. There is the challenge to increase the power and sensitivity of the surface for the electrochemical sensor. We design a virus-like hallow structure of cucoo that it holds the large amounts of p19 protein by mimicking of inherent virus (Carnation italian ringspot virus) to detect 21mir with the limit of detection (LOD = 1aM).
View Article and Find Full Text PDFTo eliminate the microbial infection from an injury site, various modalities have been developed such as dressings and human skin substitutes. However, the high amount of reactive oxygen species, microbial infection, and damaging extracellular matrix remain as the main challenges for the wound healing process. In this study, for the first time, green synthesized silver nanoparticles (AgNPs) using Teucrium polium extract were embedded in poly lactic acid/poly ethylene glycol (PLA/PEG) film to provide absorbable wound dressing, with antioxidant and antibacterial features.
View Article and Find Full Text PDFACS Appl Mater Interfaces
December 2019
Four fluorescent DNA-stabilized fluorescent silver nanoclusters (DNA-AgNCs) were designed and synthesized with differences in lengths of cytosine-rich DNA strand (as the stabilizing agent) and target-specific strand DNA aptamers for adenosine triphosphate (ATP) and cytochrome (Cyt ). After their nanohybrid formation with graphene oxide (GO), it was unexpectedly found that, depending on the composition of the base and length of the strand DNA aptamer, the fluorescence intensity of three of the nanohybrids significantly enhanced. Our experimental observations and quantum mechanical calculations provided an insight into the mechanisms underlying the behavior of DNA-AgNCs/GO nanohybrids.
View Article and Find Full Text PDFDesign of complex hollow nanostructures of two or more transition metal oxides seems to be necessary to answer the demand for novel energy storage electrodes owning outstanding performance for advanced developments of modern electronics. Herein, we develop a metal-organic frameworks (MOFs) assistance self-templated method for the synthesis of double-shell CuCoO hollow spheres as battery-type electrode material with a large surface area of 93 m g. This electrode material reveals excellent electrochemical performance with an ultrahigh specific capacity of 701 C g at 2 A g.
View Article and Find Full Text PDFMultilevel interior nanoporous CuCoO microspheres have been for the first time developed using a facile self-templated method. Electrochemical results in three- and two-electrode systems show that the double-shelled hollow microsphere electrode is a promising candidate for high-performance supercapacitors.
View Article and Find Full Text PDF3D LSG/CoNiS//LSG interdigitated microelectrodes have been firstly developed by a facile, scalable and low cost process for all-solid-state, flexible integrated asymmetric micro-supercapacitors. These devices can achieve energy densities of up to 49 W h l which is comparable to those of lead acid batteries.
View Article and Find Full Text PDFHierarchical CuCo2S4 hollow nanoneedle arrays have been firstly synthesized on a Ni foam using a facile template-free hydrothermal method and applied as novel binder-free electrodes for high-performance asymmetric supercapacitors with ultrahigh specific capacitance, high energy density, excellent rate capability and outstanding long-term cycling stability.
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