Publications by authors named "Seyyed Amin Ayatollahi-Mousavi"

Article Synopsis
  • The study evaluated the antifungal activities of 8 agents against Candida species isolated from immunocompromised patients in Iran, collected from 10 university hospitals between December 2019 and December 2021.
  • It identified 598 strains, with C. albicans being the most common, followed by C. glabrata and others, using PCR methods for identification and standard microdilution techniques for testing antifungal susceptibility.
  • Results showed that caspofungin and voriconazole had the lowest minimum inhibitory concentration (MIC) values, indicating they are the most effective treatments compared to other antifungal agents in this region, while some isolates exhibited multiazole resistance but not pan-azole resistance.
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Unlabelled: Since the authors are not responding to the editor’s requests to fulfill the editorial requirement, therefore, the article has been withdrawn. Bentham Science apologizes to the readers of the journal for any inconvenience this may have caused. The Bentham Editorial Policy on Article Withdrawal can be found at https://benthamscience.

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Aspergillus species are a major cause of life-threatening invasive infections and noninvasive diseases. This study seeks to investigate the frequency of Aspergillus species among Iranian patients and their susceptibility to seven antifungals. In a cross-sectional study, 233 Aspergillus isolates were collected from 11 university hospitals in Iran between 2018 and 2021.

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Introduction: Candidiasis infection is caused by different species of Candida, which are characterized by host immunologic weakness. Black cumin seeds (Nigella sativa) have shown an inhibitory effect against Candida albicans. In this work, the inhibitory effect of standardized extract and different fractions of Nigella sativa seeds has been evaluated on both nystatin-susceptible and resistant strain of C.

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Background And Purpose: Aflatoxins (AFs) are a group of highly toxic mycotoxins present both in the environment and in foodstuffs. The food of infants should be safe and free of various pollutants, including breast milk mycotoxins. This study aimed to measure the mycotoxin of Aflatoxin M1 (AFM1) in human milk samples obtained from lactating mothers living in Rafsanjan city, Iran.

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Background And Purpose: Aromatic waters (AWs) are therapeutic distillates, which harbor both essential oil and water-soluble components of a plant. Due to the dispersion of the light amount of essence through the AWs, they have their specific pleasant smell, taste, and medicinal properties. In Iranian traditional medicine, AW is used to treat gastrointestinal disorders.

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Background: The use of narcotics such as opium exposes addicts as susceptible targets of different diseases so that they might easily be exposed to different diseases such as fungal infections. The present study aimed to investigate the effects of addiction to opium and fungal infection on plasma levels of certain cytokines including interleukin-4 (IL-4), IL-6, IL-17, Interferon gamma (IFN-γ) and transforming growth factor-β (TGF-β).

Methods: Present study included 72 individuals who were divided into 4 groups: 1) opium-addicted with fungal infection; 2) opium-addicted without fungal infection; 3) non-opium-addicted with fungal infection; and 4) normal individuals (non-opium-addicted and non-fungal infection).

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Article Synopsis
  • Superficial and cutaneous fungal infections (SCFIs) are significant health issues, especially in tropical regions, with common types being pityriasis versicolor, dermatophytosis, and others.
  • A study in Kerman, Iran, over 10 years analyzed 1782 patients, revealing that 34.62% had SCFIs, with a higher prevalence in males and the 31-50 age range.
  • The most common type of SCFI was tinea unguium, mainly caused by T. mentagrophytes and Aspeigillus spp., highlighting the need for updated understanding and treatments of these infections.
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Background: Cell-mediated immunity (CMI) by CD4 + Th (T helper)-type cells is the predominant host defense mechanism against Oral Candidiasis (OC) in HIV-infected individuals. Weakened CMI and depletion of CD4 + T cells are the main factor contributing to the output of OC in HIV-positive individuals. The cytokines produced by Th1, Th2 and Th17 cells play a role in mediating an increased susceptibility to OC during HIV infection.

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Article Synopsis
  • Dermatophytosis is a common skin infection in humans and animals caused by dermatophyte fungi, with rising resistance to traditional antifungal drugs.
  • This study aimed to assess the antifungal effectiveness of silver nanoparticles (AgNPs) compared to griseofulvin (GR) against different strains of dermatophytes using lab tests.
  • Results showed that AgNPs had higher minimum inhibitory concentrations (MIC) than GR, indicating they were less effective, but still exhibited some antifungal activity.
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Background: Aflatoxins (AFs) are secondary hazardous fungal metabolites that are produced by strains of some Aspergillus species on food and feedstuffs. Aflatoxin B1 (AFB1) is one of the most important AF with high toxicity. Prevention of AF production and their elimination from food products is a matter of importance for many researchers in the last decades.

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Background: Fungal infections affect various parts of the body and can be difficult to treat. Aspergillus infection causes a spectrum of diverse diseases particularly in lung according to host immunity. The two major entities are invasive pulmonary aspergillosis and chronic pulmonary aspergillosis.

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Article Synopsis
  • * A study in northwest Iran examined 140 patients with otomycosis from 2009 to 2011, finding a 92% diagnosis rate, primarily in males aged 21-40, with saprophytic molds being the most frequent cause.
  • * The research highlights the need for better diagnosis and treatment methods for otomycosis in northwestern Iran, given the high prevalence identified in patients.
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In the last decades, the number of people suffering from dermatophytoses has seriously increased, which may be due to the development of resistant strains to a range of antifungal drugs. The present study was aimed to evaluate the antidermatophytic properties of eight extracts from the selected spices and herbs, which were ethno-medicinally used in Iran against Trichophyton mentagrophytes, Trichophyton interdigitale, Microsporum canis, and Microsporum gypseum (10 strain of each). The in vitro antifungal activities of the extracts from four spices and four plants were evaluated by the broth macro dilution method against four dermatophyte strains.

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Background: Human cutaneous infection caused by a homogeneous group of keratinophilic fungi called dermatophytes. These fungi are the most common infectious agents in humans that are free of any population and geographic area. Microsporum canis is a cause of dermatophytosis (Tinea) in recent years in Iran and atypical strain has been isolated in Iran.

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In this study, in vitro antidermatophytic activity against Trichophyton mentagrophytes, Trichophyton rubrum, Microsporum canis, and Microsporum gypseum was studied by disk diffusion test and assessment of minimum inhibitory concentration (MIC) using CLSI broth macrodilution method (M38-A2). Moreover, antileishmanial and cytotoxicity activity of B. vulgaris and berberine against promastigotes of Leishmania major and Leishmania tropica were evaluated by colorimetric MTT assay.

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