Machine Learning-Assisted Computational Screening of Adhesive Molecules Derived from Dihydroxyphenyl Alanine.

Marine mussels adhere to virtually any surface via 3,4-dihydroxyphenyl-L-alanines (L-DOPA), an amino acid largely contained in their foot proteins. The biofriendly, water-repellent, and strong adhesion of L-DOPA are unparalleled by any synthetic adhesive. Inspired by this, we computationally designed diverse derivatives of DOPA and studied their potential as adhesives or coating materials.

Machine-Learning Approach in Prediction of the Wettability of a Surface Textured with Microscale Pillars.

Tuning the wettability of a flat surface by introducing an array of microscale pillars finds wide applications, especially in engineering a superhydrophobic surface. The wettability of such a pillared surface is quantified by the contact angle (CA) of a water droplet. It is desired to know the CA prior to construction of pillars, in order to obviate the trial-and-errors in experimenting with many different topographies.

Molecular Simulation Study on the Wettability of a Surface Texturized with Hierarchical Pillars.

By using molecular dynamics simulation, we investigate the wettability of a surface texturized with a periodic array of hierarchical pillars. By varying the height and spacing of the minor pillars on top of major pillars, we investigate the wetting transition from the Cassie-Baxter (CB) to Wenzel (WZ) states. We uncover the molecular structures and free energies of the transition and meta-stable states existing between the CB and WZ states.

Superconducting Joining Concept for Internal Magnesium Diffusion-Processed Magnesium Diboride Wires.

A superconducting joint of unreacted monofilament internal magnesium diffusion-processed magnesium diboride (MgB) wires was fabricated by exploiting the phenomenon of magnesium diffusion into the boron layer inside the superconducting joint. Unprecedentedly, the joint was able to carry an almost identical transport current compared to the bare wire in a 2-7 T magnetic field at 20 K. The joint also exhibited very low joint resistance of 2.

Niobium-titanium (Nb-Ti) superconducting joints for persistent-mode operation.

Superconducting joints are essential for persistent-mode operation in a superconducting magnet system to produce an ultra-stable magnetic field. Herein, we report rationally designed niobium-titanium (Nb-Ti) superconducting joints and their evaluation results in detail. For practical applications, superconducting joints were fabricated by using a solder matrix replacement method with two types of lead-bismuth (Pb-Bi) solder, including PbBi as a new composition.

Development of an ion beam analyzing system for the KBSI heavy-ion accelerator.

The Korea Basic Science Institute (KBSI) has been developing a heavy ion accelerator system to accelerate high current, multi-charge state ions produced by a 28 GHz superconducting electron cyclotron ion source. A beam analyzing system as a part of the low energy beam transport apparatus was developed to select charged particles with desirable charge states from the ion beams. The desired species of ion, which is generated and extracted from the ECR ion source including various ion particles, can be selected by 90° dipole electromagnet.

First results of 28 GHz superconducting electron cyclotron resonance ion source for KBSI accelerator.

The 28 GHz superconducting electron cyclotron resonance (ECR) ion source has been developed to produce a high current heavy ion for the linear accelerator at KBSI (Korea Basic Science Institute). The objective of this study is to generate fast neutrons with a proton target via a p(Li,n)Be reaction. The design and fabrication of the essential components of the ECR ion source, which include a superconducting magnet with a liquid helium re-condensed cryostat and a 10 kW high-power microwave, were completed.

Nitrogen ion implantation into various materials using 28 GHz electron cyclotron resonance ion source.

The installation of the 28 GHz electron cyclotron resonance ion source (ECRIS) ion implantation beamline was recently completed at the Korea Basic Science Institute. The apparatus contains a beam monitoring system and a sample holder for the ion implantation process. The new implantation system can function as a multipurpose tool since it can implant a variety of ions, ranging hydrogen to uranium, into different materials with precise control and with implantation areas as large as 1-10 mm(2).

Controlled synthesis of nanoporous nickel oxide with two-dimensional shapes through thermal decomposition of metal-cyanide hybrid coordination polymers.

The urgent need for nanoporous metal oxides with highly crystallized frameworks is motivating scientists to try to discover new preparation methods, because of their wide use in practical applications. Recent work has demonstrated that two-dimensional (2D) cyanide-bridged coordination polymers (CPs) are promising materials and appropriate for this purpose (Angew. Chem.

A simulation of X-ray shielding for a superconducting electron cyclotron resonance ion source.

It is generally assumed that large amounts of x-rays are emitted from the ion source of an Electron Cyclotron Resonance (ECR) instrument. The total amount of x-rays should be strictly limited to avoid the extra heat load to the cryostat of the superconducting ECR ion source, since they are partly absorbed by the cold mass into the cryostat. A simulation of x-ray shielding was carried out to determine the effective thickness of the x-ray shield needed via the use of Geant4.

Superconducting magnet performance for 28 GHz electron cyclotron resonance ion source developed at the Korea Basic Science Institute.

A superconducting magnet for use in an electron cyclotron resonance ion source was developed at the Korea Basic Science Institute. The superconducting magnet is comprised of three solenoids and a hexapole magnet. According to the design value, the solenoid magnets can generate a mirror field, resulting in axial magnetic fields of 3.

Recondensation performance of liquid helium cryostat for a 28 GHz electron cyclotron resonance ion source.

Cryostat performance is essential for the stable operation of a superconducting magnet. A closed-cycle liquid helium cryostat was adopted for use for a superconducting electron cyclotron resonance (ECR) ion source by recondensing liquid helium vapor. The goal was to maintain the liquid helium filled reservoir at a constant level without transferring any liquid helium during the normal operation of the ECR ion source.

Development of compact linear accelerator in KBSI.

The compact linear accelerator using a 28 GHz ECRIS is under construction in KBSI, South Korea. The main capability of this facility is the production of fast neurons for the neutron radiography. The designing of a superconducting magnet, microwave transmission system, beam extraction, and plasma chamber of ECRIS were finished.

Expression of Ca-activated K Channels and Their Role in Proliferation of Rat Cardiac Fibroblasts.

Cardiac fibroblasts constitute one of the largest cell populations in the heart, and contribute to structural, biochemical, mechanical and electrical properties of the myocardium. Nonetheless, their cardiac functions, especially electrophysiological properties, have often been disregarded in studies. Ca(2+)-activated K(+) (K(Ca)) channels can control Ca(2+) influx as well as a number of Ca(2+)-dependent physiological processes.

Involvement of protein kinase A in nitric oxide stimulating effect on a BK(Ca) channel of human dermal fibroblasts.

We reported previously that a large-conductance Ca2+-activated K+ (BK(Ca)) channel constitutes a significant fraction of the K+ current in human dermal fibroblasts, and that nitric oxide (NO) increases the open-channel probability (NPo) of BK(Ca) channels via a soluble guanylate cyclase (sGC)/cyclic guanosine monophosphate (cGMP)/protein kinase G (PKG) pathway. The purpose of this study was to investigate whether the adenylate cyclase (AC)/cAMP/protein kinase A (PKA) pathway may also be involved in NO action on BK(Ca) channels in human dermal fibroblasts. Electrophysiological single-channel recordings were performed on fifth-passage cells of human penile skin cultures.