Publications by authors named "Seyma Punar"
Article Synopsis
- Behçet disease (BD) presents with various symptoms, including mucocutaneous, ocular, and vascular manifestations, and this study explores the immune-related cytokines involved in these different BD types.
- Researchers analyzed serum samples from active and remission stages of BD patients, comparing them with healthy controls, to evaluate the levels of specific cytokines like interferon γ and interleukin 35.
- The findings indicate distinct immune responses for each BD phenotype, particularly showing that the IL-17 response is less pronounced in ocular BD, suggesting a need for targeted treatments based on cytokine patterns in various BD subtypes.
Objectives: Recent studies have shown that the distribution of the tryptophan/kynurenine pathway (KP) plays a role in the development of obsessive-compulsive disorder (OCD). We aimed to reveal the relationship between CYP1A1 rs464903 and aryl hydrocarbon receptor (AhR) rs10249788 associated with the KP and interferon gamma (IFN γ) and oxidative stress in OCD.
Methods: In our study, the serum and DNAs of 150 samples, including 100 OCD patients and 50 controls, were used.