A head template for computational dose modelling for transcranial focused ultrasound stimulation.

Transcranial focused Ultrasound Stimulation (TUS) at low intensities is emerging as a novel non-invasive brain stimulation method with higher spatial resolution than established transcranial stimulation methods and the ability to selectively stimulate also deep brain areas. Accurate control of the focus position and strength of the TUS acoustic waves is important to enable a beneficial use of the high spatial resolution and to ensure safety. As the human skull causes strong attenuation and distortion of the waves, simulations of the transmitted waves are needed to accurately determine the TUS dose distribution inside the cranial cavity.

Optimum PZT Patch Size for Corrosion Detection in Reinforced Concrete Using the Electromechanical Impedance Technique.

This paper proposes the use of a 1-dimensional (1-D) electromechanical impedance model to extract proper design guidelines when selecting patch-size and frequency range for corrosion detection in reinforced concrete structures using the electromechanical impedance (EMI) technique. The theoretical results show that the sensitivity mainly lies in the peak frequencies of the impedance spectrum, while outside resonant frequencies the sensitivity levels are low, and are prone to natural variation. If the mechanical impedance ratio between the host structure and patch is too large, the peaks and thereby the sensitivity decreases.

A High-Resolution Ultrasonically Powered And Controlled Optogenetic Stimulator With A Novel Fully Analog Time To Current Converter.

In this paper, a power-efficient and high-resolution ultrasonically powered and controlled optogenetic stimulator system is proposed. The proposed system benefits from a novel fully analog Time to Current Converter (TCC) for driving a μLED for optogenetics according to time-encoded data over ultrasonic waves. The whole system including a high-efficiency active rectifier, a double-pass regulator, a burst detector, an overvoltage regulator, a reference generator and the novel TCC are designed, analyzed and simulated in transistor level in standard TSMC 0.

S-MRUT: Sectored-Multiring Ultrasonic Transducer for Selective Powering of Brain Implants.

One of the main challenges of the current ultrasonic transducers for powering brain implants is the complexity of focusing ultrasonic waves in various axial and lateral directions. The available transducers usually use electrically controlled phased array for beamforming the ultrasonic waves, which increases the complexity of the system even further. In this article, we propose a straightforward solution for selective powering of brain implants to remove the complexity of conventional phased arrays.

Ultrasonically Powered Compact Implantable Dust for Optogenetics.

This paper presents an ultrasonically powered microsystem for deep tissue optogenetic stimulation. All the phases in developing the prototype starting from modelling the piezoelectric crystal used for energy harvesting, design, simulation and measurement of the chip, and finally testing the whole system in a mimicking setup are explained. The developed system is composed of a piezoelectric harvesting cube, a rectifier chip, and a micro-scale custom-designed light-emitting-diode (LED), and envisioned to be used for freely moving animal studies.

Overvoltage Protection Circuits for Ultrasonically Powered Implantable Microsystems.

This paper presents a novel overvoltage protection technique for ultrasonically powered microsystems. The proposed idea benefits from voltage-current characteristics of the piezoelectric harvesters, and limits the amplitude of the harvested signal by regulating the current consumption of the system. For this purpose, a low-area low-power overvoltage regulator is proposed, analyzed and simulated in transistor level in standard TSMC 0.

Multi-Ring Ultrasonic Transducer on a Single Piezoelectric Disk For Powering Biomedical Implants.

This paper presents a novel ultrasonic transmitter with the ability of focusing ultrasonic waves for maximum power transmission at different depths for brain neurostimula-tor implants. The most important advantages of the proposed multi-ring ultrasonic transducer (MRUT) is its simplicity and no requirement of any lens or air cavity for focusing the ultrasonic waves. Furthermore, adjusting the focal point compared to the conventional transducers is significantly easier, especially as the location of implants may vary due to, for example, head movement or the need of using these implants at different depths.

An Implantable Ultrasonically Powered System for Optogenetic Stimulation with Power-Efficient Active Rectifier and Charge-Reuse Capability.

This paper presents a novel micro-scale ultrasonically powered optogenetic microstimulator with the vision of treating Parkinson's Disease. This system features a power-efficient active rectifier benefiting from a novel powering approach for its comparators. The main basis of the idea is to lower the Rail-to-Rail supply voltage of the comparators, thereby lowering their propagation delays.

Fabrication of a Highly Sensitive Single Aligned TiO and Gold Nanoparticle Embedded TiO Nano-Fiber Gas Sensor.

In this research, a single-aligned nanofiber of pure TiO and gold nanoparticle (GNP)-TiO were fabricated using a novel electro-spinning procedure equipped with secondary electrostatic fields on highly sharp triangular and rectangular electrodes provided for gas sensing applications. The sol used for spinning nanofiber consisted of titanium tetraisopropoxide (CHOTi), acetic acid (CHCOOH), ethanol (CHOH), polyvinylpyrrolidone (PVP), and gold nanoparticle solution. FE-SEM, TEM, and XRD were used to characterize the single nanofiber.