Iron coating was introduced as one of the novel techniques to improve physicochemical and biological properties of silver nanoparticles (AgNPs). In the current experiment, impact of iron coating on the antimicrobial potency of AgNPs was investigated against methicillin-resistance Staphylococcus aureus (MRSA). To obtain more accurate data about the antimicrobial potency of examined nanostructures, the experiment was done on the 10 isolates of MRSA which were isolated from skin lesions.
View Article and Find Full Text PDFHerbal nanoparticles (HNPs) were introduced as a novel generation of antimicrobial nanoparticles. But in the battle against superbugs we need nanostructures with boosted antimicrobial potency. So in the current experiment, for the first time a green approach was developed for the silver functionalization of HNPs which were fabricated from an antimicrobial herb Thymus vulgaris.
View Article and Find Full Text PDFCobalt-based nanoparticles (CBNPs) have recently received great attention in biomedical studies; however, the possible biotoxicity of these nanoparticles (NPs) has remained a foremost concern that should be addressed. As surface functionalization is one of the helpful proposed solutions, we aimed to apply Lipoamino acids (LAAs) as a coating agent to improve biocompatibility. To this purpose, cobalt oxide, cobalt ferrite, and iron oxide nanoparticles (IONs) were synthesized with and without 2-amino-hexadecanoic acid coating to assess the impacts of LAA coating on characteristics and biocompatibility of CBNPs in human cells and compare with IONs, a widely used magnetic NPs in biomedicine.
View Article and Find Full Text PDFDespite iron-based nanoparticles gaining huge attraction in various field of sciences and technology, their application rises ecological concerns due to lack of studies on their interaction with microbial cells populations and communities, such as biofilms. In this study, Chlorella vulgaris cells were employed as a model of aquatic microalgae to investigate the impacts of L-lysine-coated iron oxide nanoparticles (lys@IONPs) on microalgal growth and biofilm formation. In this regard, C.
View Article and Find Full Text PDFThe possibility of employing FeOOH nano-ellipsoids as a novel shape nano-based iron supplement was investigated. Ferrous sulfate and nano-ellipsoids were daily administered by gavage at low and high dosages. After 1 month of treatment, the hematologic parameters along with serum and organs' iron contents were measured.
View Article and Find Full Text PDFVarious studies were performed to fabricate self-assembling nanoobjects out of noble metals, but a few efforts were made for engineering iron-based nanorods toward sell-assembling blocks. In this regard β-FeOOH nanorods were fabricated in various sizes to achieve iron-based rod nanoblocks with self-assembling potential. Hydrolysis of ferric ions in various concentrations was successfully developed as a novel approach to control the growth of β-FeOOH crystals and tuning the length of rods in the nano range, below 100 nm.
View Article and Find Full Text PDFPichia pastoris expression system was introduced with post-translation process similar to higher eukaryotes. Preliminary studies were performed toward process intensification and magnetic immobilization of this system. In this experiment, effects of magnetic immobilization on the structure of recombinant protein were evaluated.
View Article and Find Full Text PDFZinc oxide (ZnO) nanoparticles have gained widespread interest due to their unique properties, making them suitable for a range of applications. Several methods for their production are available, and of these, controlled synthesis techniques are particularly favourable. Large-scale culturing of produces secretory carbohydrates as a waste product, which have been shown to play an important role in directing the particle size and morphology of nanoparticles.
View Article and Find Full Text PDFCell immobilization on the magnetic nanoparticles (MNPs) and magnetic harvesting is a novel approach for microalgal cells separation. To date, the effect of these nanoparticles on microalgal cells was only studied over a short period of time. More studies are hence needed for a better understanding of the magnetic harvesting proposes or environmental concerns relating to long-term exposure to nanoparticles.
View Article and Find Full Text PDFCell harvesting is one of the main expensive, labor-intensive, and energy-consuming steps in downstream processing. Cell immobilization has introduced as a valuable strategy for process intensification in biotechnological industries. Here we describe magnetic immobilization as a promising and novel technique for cell immobilization by using magnetic nanoparticles.
View Article and Find Full Text PDFMagnetic immobilization as a novel technique was used to immobilize recombinant (GS115 Albumin) cells to produce human serum albumin (HSA). In this regard, magnetic nanoparticles (MNPs) coated with amino propyl triethoxy silane (APTES) were synthesized. cells were decorated with MNPs via nonspecific interactions.
View Article and Find Full Text PDFFeOOH nanoparticles are commonly synthesized at very high temperature and pressure that makes the process energy consuming and non-economic. Recently, novel approaches were developed for the fabrication of these particles at room temperature. But, the main problem with these methods is that the prepared structures are aggregates of ultra-small nanoparticles where no intact separate nanoparticles are formed.
View Article and Find Full Text PDFZinc is one of the essential trace elements, and plays an important role in human health. Severe zinc deficiency can negatively affect organs such as the epidermal, immune, central nervous, gastrointestinal, skeletal, and reproductive systems. In this study, we offered a novel biocompatible xanthan gum capped zinc oxide (ZnO) microstar as a potential dietary zinc supplementation for food fortification.
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