Publications by authors named "Seyedeh Nazila Hosseini"
High Precision Ping-Pong Auto-Zeroed Lock-in Fluorescence Photometry Sensor.
Vahid Khojasteh Lazarjan Marie-Eve Crochetiere Mehdi Noormohammadi Khiarak Saeed Ghaneei Aarani Seyedeh Nazila Hosseini
IEEE Trans Biomed Circuits Syst
October 2024
Article Synopsis
- The paper introduces a high-precision CMOS fluorescence photometry sensor featuring a novel lock-in amplification method that enhances performance while minimizing power consumption.
- The sensor design integrates two photodiodes, operates at 1 kHz, has a dynamic range of 42 dB, and successfully detects light powers from 8 nW to 24 µW, all within a compact 3D-printed housing.
- Experimental results demonstrate the sensor's effectiveness in real-time biomarker detection, achieving a sensitivity of 1:100,000 and revealing its capability to detect varying densities of NIH3T3 mouse cells.
Rapid, high-sensitivity, and real-time characterization of microorganisms plays a significant role in several areas, including clinical diagnosis, human healthcare, early detection of outbreaks, and the protection of living beings. Integrating microbiology and electrical engineering promises the development of low-cost, miniaturized, autonomous, and high-sensitivity sensors to quantify and characterize bacterial strains at various concentrations. Electrochemical-based biosensors are receiving particular attention in microbiological applications among the different biosensing devices.
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