Background: Hand eczema (HE) is a common and heterogeneous condition. It has a wide range of etiologies and clinical manifestations. In this study the efficacy of triamcinolone 0.
View Article and Find Full Text PDFMotivation: Proteins accomplish cellular functions by interacting with each other, which makes the prediction of interaction sites a fundamental problem. As experimental methods are expensive and time consuming, computational prediction of the interaction sites has been studied extensively. Structure-based programs are the most accurate, while the sequence-based ones are much more widely applicable, as the sequences available outnumber the structures by two orders of magnitude.
View Article and Find Full Text PDFThe present study examined the ability of Quercus castaneifolia C.A.M.
View Article and Find Full Text PDFViscum album L. (mistletoe) is a semiparasitic plant of the Santalaceae family. A valuable group of bioactive compounds in mistletoe are triterpene acids (TTAs), which possess anti-inflammatory and anticancer properties.
View Article and Find Full Text PDFSeveral proteins work independently, but the majority work together to maintain the functions of the cell. Thus, it is crucial to know the interaction sites that facilitate protein-protein interactions. The development of effective computational methods is essential because experimental methods are expensive and time-consuming.
View Article and Find Full Text PDFCellular functions are governed by proteins, and, while some proteins work independently, most work by interacting with other proteins. As a result it is crucially important to know the interaction sites that facilitate the interactions between the proteins. Since the experimental methods are costly and time consuming, it is essential to develop effective computational methods.
View Article and Find Full Text PDFMistletoe (Viscum album L.) is a hemiparasitic plant that absorbs water and nutrients from the host tree. Mistletoe contains two groups of cytotoxic, immunomodulatory and antitumor proteins, viscotoxins and lectins.
View Article and Find Full Text PDFBackground: Timely and accurate diagnosis of genetic diseases can lead to proper action and prevention of irreparable events.
Objective: In this work we propose an integrated genetic-neural network (GNN) to improve the prediction risk of trisomy diseases including Down's syndrome (T21), Edwards' syndrome (T18) and Patau's Syndrome (T13).
Methods: A dataset including 561 pregnant were created.
Introduction: Cancer stem cells (CSCs) are a theorized subset of cells within the tumor that is thought to drive disease recurrence and metastatic spread. The aim of this study is to investigate mRNA and protein levels of ganglioside GD2 synthase (GD2S), in breast cancer (BC) patients.
Methods: 65 PBMCs of preoperative BC patients without chemotherapy were compared to PBMCs after chemotherapy and controls.
Objective: Vitiligo is a common, autoimmune disease that results in the destruction of the melanocytes and manifests as depigmented macules on various areas of the skin. Numerous treatment options have been proposed for vitiligo. The purpose of this study was to compare the efficacy of microneedling plus topical pimecrolimus 1% versus the sole use of topical pimecrolimus 1% for the treatment of vitiligo.
View Article and Find Full Text PDFBackground: The relation between air pollution and cardiovascular diseases (CVDs) risk factors, especially blood pressure (BP) levels, has been less frequently assessed. The aim of this study was evaluating the association between air pollutants of less than 2.5 µm [particulate matter (PM2.
View Article and Find Full Text PDFGreen vegetation improvement is an economical strategy to mitigate dust air pollution. The anticipated performance index (API) is considered a main criterion to select the suitable plants of urban forests. API is calculated by taking air pollution tolerance index (APTI) and socio-economic and biological aspects into account.
View Article and Find Full Text PDFJMIR Med Inform
July 2020
Background: Asthma is commonly associated with chronic airway inflammation and is the underlying cause of over a million deaths each year. Crocus sativus L, commonly known as saffron, when used in the form of traditional medicines, has demonstrated anti-inflammatory effects which may be beneficial to individuals with asthma.
Objective: The objective of this study was to develop a clinical prediction system using an artificial neural network to detect the effects of C sativus L supplements on patients with allergic asthma.
The Hyrcanian Forest region is rich in relict species, and endemic and endangered species. Although there are concerns about climate change, its influence on tree species in the Hyrcanian forests in the north of Iran is still unidentified. Taxus baccata is among the few conifer species found in the region, and the present study aims to evaluate the potential impact of climate change on the distribution of T.
View Article and Find Full Text PDFStaphylococcus lugdunensis is a coagulase-negative Staphylococcus species that may cause various infections with unusual severity. In spite of the administration of various antibiotics, infections caused by such bacteria are become resistant significantly. Transmission of antibiotic resistance genes, especially by Integron structures, exacerbates the prevalence of resistant strains.
View Article and Find Full Text PDFBackground: Leishmaniasis is an infectious disease caused by an intracellular parasite of and is transmitted through the female sandflies bite and may lead to severe skin lesions. Although drugs such as antimony compounds are available, their side effects such as toxicity, low efficacy, and emergence of resistance have raised the importance of effective replacement. Imatinib, as an inhibitor of tyrosine kinase (TK) of , stops abnormal function of TK such as Bcr-Abl through assembling into transmembrane pores in a sterol-dependent manner.
View Article and Find Full Text PDFSoil contaminated with heavy metals (HMs) is a serious problem throughout the world that threatens all living organisms in the soil. Therefore, large-scale remediation is necessary. This study investigated a new combination of remediation techniques on heavy metal contaminated soil, phytoremediation, and soil amendment with nano-sized zero-valent iron (nZVI) and rhizosphere microorganisms.
View Article and Find Full Text PDFObjective: We hypothesized that silage additives may alter the undigested neutral detergent fiber (uNDF) content through ensiling. Therefore, urea and formic acid were applied to corn, whole barley crop (WBC) and alfalfa to change uNDF content of the ensiled forages.
Methods: Six experimental diets at two groups of high uNDF (untreated corn and alfalfa silages [CSAS] and untreated whole barley and alfalfa silages [BSAS]) and low uNDF (urea-treated corn silage+untreated alfalfa silage [CSUAS], urea-treated whole barley silage+untreated alfalfa silage [BSUAS], untreated corn silage+formic acid-treated alfalfa silage [CSASF], and untreated whole barley silage+formic acid-treated alfalfa silage [BSASF]), were allocated to thirty-six multiparous lactating Holstein dairy cows.
Background: Androgenetic alopecia is the commonest type of alopecia affecting over half of men and women. Low-level light therapy is a new technique for stimulating hair growth in both genders.
Aims: To overcome the shortcomings of previous epidemiological studies and a lack of controlled clinical trials on the subject, this study compared the effectiveness of adding low-level light therapy to minoxidil topical solution in the treatment of androgenetic alopecia in patients presenting to two skin clinics in Isfahan, Iran during 2014-2015.
In the present work, vertically aligned carbon nanotube (VA-CNT) sheets were synthesized via pyrolysis of polybenzimidazole (PBI)-Kapton inside the pores of anodized aluminum oxide (AAO). The synthesized VA-CNT sheets were then evaluated for the desalination of salty water. The results indicated that the VA-CNT sheets were effective for application as an adsorbent for desalination of salty water due to their high adsorption capacity, with no loss of CNTs in the treated water.
View Article and Find Full Text PDFThe present study deals with application of the weighted linear combination method for zoning of forest fire risk in Dohezar and Sehezar region of Mazandaran province in northern Iran. In this study, the effective criteria for fires were identified by the Delphi method, and these included ecological and socioeconomic parameters. In this regard, the first step comprised of digital layers; the required data were provided from databases, related centers, and field data collected in the region.
View Article and Find Full Text PDFPediatr Exerc Sci
February 2018
Purpose: Biochemical markers such as cardiac troponin I (cTnI) and N-terminal pro B-type natriuretic peptide (NT-proBNP) have become indispensable tools for the diagnosis of myocardial injury, providing highly sensitive and specific information about cardiac cell damage and wall stress. The purpose of the present research was to examine the response of cardiac biomarkers to a soccer game in adolescent male soccer players.
Methods: Twenty-two trained adolescent male soccer players (14-16 y) were selected in a purposive manner.
Soil organic carbon (SOC) contains a considerable portion of the world's terrestrial carbon stock, and is affected by changes in land cover and climate. SOC modeling is a useful approach to assess the impact of land use, land use change and climate change on carbon (C) sequestration. This study aimed to: (i) test the performance of RothC model using data measured from different land covers in Hyrcanian forests (northern Iran); and (ii) predict changes in SOC under different climate change scenarios that may occur in the future.
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