Publications by authors named "Seyed-Mohammad Mousavi"

Article Synopsis
  • Albendazole has limited effectiveness against Echinococcosis, prompting research into improving treatment outcomes, particularly through the use of Sulfonated Graphene Oxide (S-GO) as a nanocarrier.
  • In the study, protoscoleces were treated with different agents, and it was found that S-GO combined with Albendazole (S-GO-Albendazole) enhanced gene expression and was 18% more effective at reducing the survival of protoscoleces compared to Albendazole alone.
  • Despite S-GO's lack of strong lethality on its own, it significantly improved Albendazole's efficacy, suggesting its potential as a nanocarrier, but further studies are necessary to assess
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Introduction: This study aimed to investigate the synergistic effects of dietary selenium nanoparticles (Se-NPs) and vitamin C (VC) on growth, body composition, antioxidant defense, immunity, and serum biochemical indexes of common carp (Cyprinus carp) juveniles.

Methodology: The test diets were supplemented with three levels of Se-NPs (0, 0.5, and 1 mg/Kg) and three levels of VC (0, 500, and 1000 mg/Kg): the basal diet without supplemental Se-NPs and VC (VCSeNPs; control), 0.

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  • The study evaluated the expression of specific genes in different regions (protoscoleces, germinal layer, neck, and sucker) of adult parasites, aiming to understand their role in development.
  • Conducted at Kerman University in 2018, researchers cultured protoscoleces to obtain strobilated worms, isolated various regions for analysis, and used RT-qPCR and immunohistochemistry for gene expression profiling.
  • Results indicated that certain gene expressions varied significantly across different regions, suggesting their potential role in the differentiation of the parasite throughout its life cycle.
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The aquaculture industry frequently employs various slaughter methods that subject fish to inhumane conditions, resulting in significant suffering. This study examined the effects of electrical method on the welfare of farmed fish () compared to air asphyxiation. Fish captured with electricity exhibited calm behavior until death, in contrast to fish treated with air asphyxiation, which exhibited violent responses within 4 minutes of capture.

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Purpose: Cardiometabolic disease (CMD) is increasing along with its predisposing factors and adverse consequences. As gut microbiota dysbiosis is established in these patients, fecal microbiota transplantation (FMT), which alters the bacterial composition of the intestine, supposedly can help improve cardiometabolic disturbances. We conducted a systematic review and meta-analysis evaluating the impact of FMT on the cardiometabolic parameters and gut microbiota composition of patients experiencing at least one cardiometabolic issue.

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Purpose: Only a few studies have studied the association between plant-based dietary index (PDI) and the prevalence of obesity. The purpose of this study was to investigate the association between PDI and the prevalence of general and abdominal obesity in a large sample of Iranian adults.

Methods: The current cross-sectional study was performed from 2010 to 2012 in Isfahan, Iran.

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PLACK syndrome is a relatively recently defined generalized peeling skin syndrome that has been reported with major skin manifestations and sometimes atypical features. We report the case of a 5-year-old boy with PLACK manifestations. Whole exome sequencing and subsequent Sanger sequencing identified a putative splice variant c.

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Background: The Coronavirus disease 2019 (COVID-19) pandemic has had a devastating impact on health systems, food supplies, and population health. This is the first study to examine the association between zinc and vitamin C intakes and the risk of disease severity and symptoms among COVID-19 patients.

Methods: This cross-sectional study included 250 recovered COVID-19 patients aged 18-65 years from June to September 2021.

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Article Synopsis
  • Echinococcus granulosus has a complex life cycle that relies on specific transcription factors (TFs) and miRNAs to regulate gene expression during its development.
  • The study identified 394 unique TFs and 818 differentially expressed genes, leading to a network involving 8 specific miRNAs and 8 TFs that influence the parasite’s metabolic processes.
  • By validating TF expression through quantitative polymerase chain reaction, the research highlights potential targets for interrupting the parasite's development and controlling dog infections.
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Purpose: Metabolic syndrome (MetS) is a major public health concern that increases the risk of cardiovascular disease and mortality. In previous studies of MetS management, low-carbohydrate diets have been strongly emphasized, despite the fact that many apparently healthy individuals have difficulties adhering to these diets on a long-term basis. The purpose of the present study was to elucidate the effects of a moderately restricted carbohydrate diet (MRCD) on cardiometabolic risk factors in women with MetS.

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The aim of this study was to investigate the synbiotic effects of (PA) and isomaltooligosaccharide (IMO) on the performance of juvenile common carp (). A total of 360 fish (17.22 ± 0.

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There is an equivocal and inconsistent association between legume consumption and health outcomes and longevity. The purpose of this study was to examine and quantify the potential dose-response relationship between legume consumption and all-cause and cause-specific mortality in the general population. We conducted a systematic literature search on PubMed/Medline, Scopus, ISI Web of Science, and Embase from inception to September 2022, as well as reference lists of relevant original papers and key journals.

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Article Synopsis
  • Cystic echinococcosis (CE) is a significant global health issue caused by a type of tapeworm, with unclear mechanisms of how the disease develops in its intermediate hosts.
  • In this study, researchers cultivated protoscoleces (the larval stage of the parasite) for 105 days to observe the effects of growth factors insulin and BMP-4 on the morphology and biology of microcysts.
  • Findings showed that treatment with insulin and BMP-4 led to increased microcyst formation and size, reduced apoptosis, and altered calcium deposition, indicating these hormones potentially influence the progression of the disease.
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Introduction: Multiple sclerosis (MS) is characterized by the destruction of the blood-brain barrier, loss of myelin sheath, and contribution of inflammatory interleukins such as TNF-alpha, interleukin-17, and interleukin-6.

Methods: The current study investigated the effect of antigen B of hydatid cyst fluid on the reduction of anti-inflammatory cytokines and nerve conduction velocity in rats with experimental autoimmune encephalomyelitis (EAE)-induced MS. After isolation of antigen B from sterile cyst fluid, the rats were randomly divided into four groups: saline, EAE, EAE + teriflunomide (EAE + TF), and EAE + antigen B (EAE + AngB).

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Background: Metabolic syndrome (MetS) is a group of risk factors that increase the risk of death and a variety of chronic diseases. Recent studies have indicated that the imbalance of gut microbiota might contribute to development and progression of metabolic syndrome. Carbohydrate restriction in the diet has been proven to be one of the most effective methods in the management of metabolic syndrome, even in the absence of weight loss.

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Introduction: Nausea and vomiting are common complaints among patients who refer to the emergency department with head trauma. This study aimed to compare the effect of aromatherapy with isopropyl alcohol versus intravenous ondansetron in management of mild head trauma nausea and vomiting.

Methods: This randomized clinical trial was conducted on patients with isolated mild head trauma complaining of nausea and vomiting who were referred to emergency department during a 6-month period.

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Background: Single nucleotide polymorphisms have been implicated in various diseases, most notably non-communicable diseases (NCDs). The aim of this study was to review available evidence regarding associations between polymorphisms and NCDs in the Iranian population.

Methods: A comprehensive search was conducted through PubMed/Medline and Scopus databases up to December 2021, as well as reference lists of pertinent articles and key journals.

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Background And Aims: Fruits and vegetables are rich in fiber and a good source of anti-inflammatory and immune-boosting vitamins, minerals, and antioxidants. We investigated the association between fruits, vegetables, and fiber intake and severity of COVID-19 and related symptoms in hospitalized patients.

Methods: A total of 250 COVID-19 hospitalized patients aged 18 to 65 years were recruited for this cross-sectional study in Kashan, Iran, between June and September of 2021.

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Cystic echinococcosis or hydatid disease is one of the most important zoonotic parasitic diseases caused by Echinococcus granulosus, a small tapeworm harbored in the intestine of canines. There is an urgent need for applied genetic research to understand the mechanisms of pathogenesis and disease control and prevention. However, the lack of an effective gene evaluation system impedes direct interpretation of the functional genetics of cestode parasites, including the Echinococcus species.

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Background: The coronavirus disease 2019 seems to change antibiotic resistance pattern. Certain conditions in the Covid-19 era may be contributing to the rise of antimicrobial resistance (AMR). Due to the limited information on the impact of Covid-19 on antimicrobial resistance (AMR), the purpose of this research was to investigate the trend in antimicrobial resistance changes of E.

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Article Synopsis
  • The study investigates the link between adherence to the Mediterranean diet (MD) and the severity of COVID-19 symptoms in Iranian hospitalized patients.
  • A total of 250 COVID-19 patients were assessed using dietary questionnaires, and results showed that those with higher MD adherence had significantly lower inflammatory markers and a reduced likelihood of severe COVID-19.
  • The findings suggest that following the Mediterranean diet may lead to milder symptoms, shorter hospital stays, and overall better health outcomes for COVID-19 patients.
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This study aimed to quantitatively summarize earlier findings on the association between whole grain (WG) intake and type 2 diabetes (T2D) risk. We searched related keywords on PubMed/Medline, Scopus, and Google Scholar up to October 2021. Prospective observational studies investigating the association between WG intake and risk of T2D were included.

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Background And Aims: Magnesium is an anti-inflammatory mineral that plays a role in the innate immune system, and the relaxation of bronchial smooth muscle warrants additional attention in COVID-19. This study examined the association between magnesium intake and COVID-19 severity and related symptoms in hospitalized patients.

Methods: A cross-sectional study was done enrolling 250 COVID-19 patients aged 18 to 65 years.

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Objective: To investigate the relationship between salivary amylase level and computed tomoraphy (CT scan) findings in patients with isolated mild traumatic Brain Injury (mTBI) referred to the emergency department of Shahid Hasheminejad Hospital.

Methods: Patients with isolated mTBI and indication for brain CT scan who referred to the trauma center of Shahid Hasheminejad Hospital, Mashhad, Iran in 2019 were included in a cross-sectional study. In the initial examination, the patient's level of consciousness was measured using the Glasgow Coma Scale (GCS), and saliva samples were taken at the emergency department to determine the level of salivary amylase.

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Background: Airway management is an important skill for emergency physicians, and confirmation of correct endotracheal tube (ETT) placement is a crucial component of airway management.

Objectives: Due to the occurrence of incorrect ETT positioning in emergency departments, the present study aimed to compare the diagnostic sensitivity of ultrasound using suprasternal and subxiphoid methods for confirming the correct placement of ETT compared to capnography.

Methods: This cross-sectional study was conducted by examining patients requiring intubation.

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