/ insight into the effect of titanium dioxide nanoparticle on serum paraoxonase 1 activity in rat.

Serum paraoxonase1 (PON1) has special function in human body organism including the antioxidant and anti-atherogenic properties. In the present study, the effect of TiO nanoparticles on the activity and structure of the PON1 has been evaluated through and methods. After treatments of the rats with different doses of TiO NPs, blood samples were collected and serum PON1 activity was measured by phenylacetate and paraoxon as substrate.

Effects of Pioglitazone On the Lipid Profile, Serum Antioxidant Capacity, and Gene Expression in Mouse Brown Adipose Tissue.

Background: Pioglitazone increases insulin sensitivity and improves glycemic control in type 2 diabetics. In this study, we evaluated the effects of pioglitazone on the uncoupling protein 1 (UCP1) expression in mouse brown adipose tissue (BAT), and on recovery from oxidative stress due to a high-fat diet.

Methods: 30 mice were divided into three groups: group 1 received a normal diet, group 2 received a high-fat diet, and group 3 received a high-fat diet plus 30 mg/kg pioglitazone.

Comparison of Pure Palm Olein Oil, Hydrogenated Oil-Containing Palm, and Canola on Serum Lipids and Lipid Oxidation Rate in Rats Fed with these Oils.

Background: Due to increased consumption of canola oil and hydrogenated oil containing palm and palm olein, and their possible effects on serum lipoproteins, the present study was conducted to determine the effects of these oils on lipids and lipid oxidation level.

Methods: In this experimental study, 88 Wistar rats were randomly assigned to four groups. Control group (A) was on a normal diet.