Publications by authors named "Seyed Saied Homami"
To suppress HepG2 liver cancer cells, a nanocarrier (NC) consisting of FeO, Gelatin (G), and Starch (S) was synthesized and characterized for targeted delivery of Quercetin (QC) drug. The spectra obtained from X-ray diffraction (XRD) and Fourier transform infrared (FTIR) demonstrated that the nanoparticles (NP) in the NC are well-interconnected to each other and have formed a regular structure. Also, field emission scanning electron microscopy (FE-SEM) indicates a smooth and homogeneous surface of the synthesized NC.
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- Chemotherapy often leads to adverse effects, prompting the exploration of natural drugs like Quercetin (QC) and targeted delivery systems.
- Researchers encapsulated QC in a synthesized nanocarrier made of FeO, starch, and polyvinyl alcohol (FeO/S/PVA), which showed effective drug loading and release properties.
- The study demonstrated that this nanocarrier effectively delivered QC to HepG2 cancer cells, showing promising results in cell viability assays, indicating its potential as a targeted cancer treatment.
A sustainable hybrid material based on carbonized cotton cloth/zeolite imidazolate framework-71/FeO/polythionine (CC/ZIF-71/FeO/PTh) was synthesized and applied in ultrasound-assisted dispersive magnetic solid-phase extraction (USA-DMSPE) followed with high performance liquid chromatography-ultraviolet detection (HPLC-UV) for simultaneous quantitation of diclofenac (DIC) and febuxostat (FEB) in human plasma. The surface of CC was modified with nanoarrays of zeolite imidazolate framework-71/FeO/Polythionine. At first, an synthesis of ZIF-71 in the presence of CC was carried out, and followed with magnetization process and oxidative polymerization of thionine.
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