Publications by authors named "Seyed Reza Fatemi Tabatabaie"
Context: Maternal exposure to silver nanoparticles (AgNPs) affects neurobehavioral reflexes and spatial memory formation in offspring. Although the transmission of AgNPs into the brain has been reported, its toxic effect on dopamine metabolism in the brain of offspring has not been studied so far.
Objective: The aim of the present study was to investigate the expression levels of tyrosine hydroxylase (TH) and monoamine oxidase A (MAO-A) genes in the brain of offspring exposed in utero to various concentrations of AgNPs.
Article Synopsis
- PCOS is the most common endocrine disorder in women, and during the study, ovarian chemerin levels increased due to PCO induction, which was linked to insulin resistance and heightened hormone production.
- Treatment with metformin and pioglitazone reduced ovarian chemerin expression and improved both insulin resistance and abnormal steroid levels in rats with PCO.
- The findings suggest that targeting chemerin expression could be a potential new treatment strategy for managing PCO in patients using these insulin-sensitizing drugs.