Effect of Ibuprofen on IL-1β, TNF-α and PGE2 levels in periapical exudates: a double blinded clinical trial.

Background: Bone resorption is one of the main features of inflammatory periapical lesions and is mainly mediated by interleukin-1 beta (IL-1β), tumor necrosis factor-alpha (TNF-α) and prostaglandin-E2 (PGE2). Recent investigations of these lesions revealed that pharmacological modulation may be possible.

Objective: The aim of this study was to evaluate the effect of Ibuprofen on IL-1β, TNF-α and PGE2 levels in periapical exudates and compare the results with a group of placebo control.

The effect of post space preparation in teeth obturated with Mineral Trioxide Aggregate evaluated using a fluid filtration system.

The aim of this study was to evaluate the seal of a 4-mm Mineral Trioxide Aggregate (MTA) filling after post space preparation. Forty single-rooted premolar teeth without curved root anatomy and fractures were selected. The root length was standardized to 12 mm by removing excess from the apical end.

Bacterial microleakage and post space timing for two endodontic sealers: an in vitro study.

Aim: The effects of immediate versus delayed post space preparation on the apical seal using resin and zinc oxide eugenol (ZOE) sealers were compared by a bacterial leakage model.

Methodology: Eighty-six premolars were randomly assigned to four experimental groups of 20 teeth. Three teeth were assigned to each control group, either positive (filled only with guttapercha) or negative (not obturated but root surfaces completely covered).

Effect of pretreatment prednisolone on postendodontic pain: a double-blind parallel-randomized clinical trial.

Introduction: Effective management of endodontic pain represents a continuing challenge. This study evaluates the use of a preoperative, single oral dose of prednisolone for the prevention and control of postendodontic pain.

Methods: Forty patients were randomly assigned to 2 groups, placebo and prednisolone (30 mg).

A comparative study of density of obturated root canals by conventional and mechanical lateral condensation techniques.

Background: The purpose of this study was to compare the weight of root canal filling material used in a new lateral condensation technique named mechanical lateral condensation (MLC) with that of conventional lateral condensation technique (LC). This new technique uses reciprocal handpiece.

Methods: In this experimental study, 40 human extracted straight canine teeth were used.

Comparison of removed dentin thickness with hand and rotary instruments.

Introduction: The aim of this study was to evaluate the amount of dentine removed after canal preparation using stainless steel (SS) hand instruments or rotary ProFile instruments.

Materials And Methods: Thirty-six extracted human teeth with root canal curvatures less than 30º were embedded in clear polyester resin. The roots were cut horizontally at apical 2, 4 and 7 mm.

A comparative study of apical microleakage using the conventional lateral condensation and mechanical lateral condensation techniques.

Introduction: This study compared apical dye penetration using lateral condensation technique (LC) and LC technique with a reciprocal handpiece (mechanical lateral condensation or MLC) as a new method.

Materials And Methods: Forty-eight human extracted straight canine teeth were used. After crown amputation, the teeth were randomly divided into four experimental groups of 10 teeth each and two negative and positive control groups of 4 teeth each.