Publications by authors named "Seyed Mehdi Marashi"
Article Synopsis
- Dengue virus (DENV) poses a significant global health threat, affecting about two-thirds of the world's population, primarily transmitted by mosquitoes and leading to severe illnesses like dengue shock syndrome.
- The severe manifestations of DENV are associated with inflammatory responses and the activation of platelets and leukocytes, which contribute to complications like hypovolemic shock and organ failure.
- Current research is focused on understanding the interaction between platelets and leukocytes in DENV's pathogenesis and whether anti-inflammatory or anticoagulant treatments can alleviate severe symptoms and prevent further tissue damage.
Loc646329 sponges miR-21 to reduce RAS/MAP kinase signaling pathway in oral squamous cell carcinoma (OSCC).
Akhtar Adereh Parya Amini Azadeh Fateh Ferdos Faghihkhorasani Nastaran Khdakarim Seyed Mehdi Marashi
Naunyn Schmiedebergs Arch Pharmacol
December 2024
Oral squamous cell carcinoma (OSCC) is a prevalent and aggressive form of head and neck cancer. Emerging evidence suggests that microRNAs (miRNAs) play a crucial role in the development and progression of OSCC. In particular, miR-21 has been implicated in various cellular processes, including proliferation, apoptosis, and invasion; it could be a potential therapeutic target for OSCC.
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