Evaluation of Glutathione S-transferase T1 (GSTT1) deletion polymorphism on type 2 diabetes mellitus risk in a sample of Yazdian females in Yazd, Iran.

Background: There has been much interest in the role of free radicals and oxidative stress in the pathogenesis of diabetes mellitus (DM). The aim of this study was to assess the possible association between genetic polymorphisms of the glutathione S-transferase-mu (GSTT1) and the risk of the development of DM in a sample of Yazdian females in Yazd, Iran.

Methods: This was a case-control study in which GSTT1 polymorphism was genotyped in 51 randomly selected DM patients and 50 randomly selected healthy controls among Yazdian females whose ages ranged from 40 to 70.

Effect of Off-Pump Coronary Artery Bypass Surgery on Patients' Quality of Life.

Background: Off-pump coronary artery bypass (OPCAB) surgery is a common technique used to control the incidence of myocardial ischemia and to increase the lifespan of patients with coronary artery disease (CAD). There is still considerable controversy about effect of OPCAB on patients' quality of life. The purpose of this study was to determine the effect of OPCAB on different aspects of the patients' quality of life.