Fronto-Orbital Osteoblastoma With Unilateral Exophthalmos: A Rare Presentation and Review of Diagnostic Challenges.

Osteoblastoma is an uncommon benign bone tumor rarely involving the craniofacial skeleton. Manifestations in the fronto-orbital region are exceptionally rare. A 19-year-old man presented with persistent headache, nausea, vomiting, right eye pain, and longstanding right exophthalmos.

Giant odontoma: A systematic scoping review and case report.

Introduction And Importance: The most common type of odontogenic tumor is odontoma. Cases with at least one dimension (sagittal, axial, or coronal) ≥30 mm were categorized as giant odontomas. This study aimed to provide a scoping review of giant odontoma and present a case report.

Psychometric properties of the Iranian version of the dissociative experiences measure, Oxford (DEMO).

Backgrounds: Dissociative experiences are described as crucial psychological mechanisms involving the organism's responses to severe psychological traumas and unpleasant past experiences. This research was conducted to examine the psychometric properties of the Dissociative Experiences Measure, Oxford (DEMO) in the Iranian general population.

Methods: This study used cross-sectional correlation, and the statistical population consisted of Iranians over 15 years old.

Tuning the optical, electrical, and structural properties of Cu-DLC thin films via simultaneous DC-RF unbalanced magnetron sputtering.

This study evaluates the deposition of diamond-like carbon (DLC) films with copper impurities on a glass substrate using simultaneous direct current (DC) and radio frequency (RF) magnetron sputtering. The structural, optical, electrical, and mechanical properties, as well as the surface topography of the films, were investigated under various DC power levels using Raman spectroscopy, ellipsometry, UV-VIS, I-V measurements, nanoindentation, AFM, and FESEM. Results indicate that increasing the DC power to the graphite target from 60 to 120 , while maintaining a constant 10  of RF power to the copper target, enhances the optical absorption coefficient of the films and increases the optical bandgap from 0.

Non-spike protein inhibition of SARS-CoV-2 by natural products through the key mediator protein ORF8.

The recent pernicious COVID-19 pandemic is caused by SARS-CoV-2. While most therapeutic strategies have focused on the viral spike protein, Open Reading Frame 8 (ORF8) plays a critical role in causing the severity of the disease. Nonetheless, there still needs to be more information on the ORF8 binding epitopes and their appropriate safe inhibitors.

Chili pepper consumption and duration of fissure symptoms onset are associated with perianal fistula development among patients with anal fissure: a case-control study.

Background: Perianal fistula is one of the complications of deepened anal fissure. The present case-control study aimed to assess the risk factors of fissure-associated fistulas due to the limited available evidence.

Methods: Patients with fissure-associated fistulas were considered as case, and patients with anal fissure who were undergoing medical treatment without any previous anorectal surgeries were considered as control group.

New structure of step-up DC-DC converter based on three winding coupled inductor with high gain capability featuring integrated renewable energy applications.

This research presents an innovative design for a non-isolated DC-DC converter, which utilizes a single switch in a high step-up configuration. The key element of this design is a three-winding coupled inductor (TWCI), which plays a crucial role in achieving a substantial voltage increase. By utilizing a low duty cycle, the converter minimizes conduction losses in the power switch, resulting in enhanced efficiency.

Local Application of Honey for Postoperative Pain Management and Associated Outcomes Following Tonsillectomy in Children: A Systematic Review and Meta-Analysis.

Background: This study investigates the effect of locally applied honey on pain intensity, analgesia consumption, pain relief and nighttime awakenings in children following tonsillectomy, addressing conflicting evidence and the lack of differentiation between adult and paediatric populations in previous reviews.

Methods: A systematic search was conducted across multiple databases, including Cochrane Library, ClinicalTrials.gov, MEDLINE, Web of Science and Google Scholar.

Design and optimization of IgG avidity test for differentiating acute from chronic human toxoplasmosis: A systematic review and meta-analysis.

Toxoplasmosis which is caused by T. gondii, is common among humans and animals. T.

Effect of Vitamin D Supplementation on the Treatment of Pulmonary Tuberculosis Patients in Different Polymorphisms of the Vitamin D Receptor.

Background: Vitamin D leads to the activation of macrophages and limitation of intracellular growth of Mycobacterium tuberculosis. Vitamin D receptor (VDR) gene polymorphisms can facilitate the development of tuberculosis (TB). Therefore, the present study aimed to investigate the effect of vitamin D supplementation on response to treatment in patients with pulmonary TB for different VDR polymorphisms.

TNF-α-Induced NF-κB Alter the Methylation Status of Some Stemness Genes in HT-29 Human Colon Cancer Cell.

Background: Acquisition of stem-like properties requires overcoming the epigenetic barrier of differentiation and re-expression of several genes involved in stemness and the cell cycle. DNA methylation is the classic epigenetic mechanism for de/differentiation. The writers and erasers of DNA methylation are not site-specific enzymes for altering specific gene methylation.

Sex differences in hypertension incidence and risk factors: a population-based cohort study in Southern Iran.

Background: Hypertension (HTN) is a major global public health concern. This study aims to identify gender differences to inform more effective prevention strategies and targeted management approaches.

Methods: This prospective cohort study included 7,710 participants aged 40 to 70 years, with a mean follow-up duration of 5.

Combination of methanolic-extract with cisplatin can induce antioxidant activity and apoptosis in HeLa and Caski cells.

Background: Cisplatin-based chemotherapy as a common therapeutic regimen for cervical cancer patients, is becoming more and more ineffective due to high resistance. This urges the need for introducing novel metabolics such as botanical drugs with the capacity to increase the cisplatin effectiveness. In that regard, here we investigated the anticancer effects of the Cisplatin- combination in cervical cancer cell lines.

Effect of lecithin on the antioxidant mechanism of action of fucoidan in stripped bulk sunflower oil and respective oil in water emulsion.

The objective of this study was to investigate the antioxidant mechanism of action of fucoidan in sunflower oil and its oil-in-water emulsion. In addition, the effect of lecithin on the antioxidant mechanism of action of fucoidan in sunflower oil was investigated. In sunflower oil, fucoidan at 0.

The correlation between indirect calorimetry data and the metabolic syndrome development in men and women.

Objectives: To investigate the indirect calorimetric findings in subjects with Metabolic Syndrome (MetS) compared to those without MetS and explore the potential parameters for predicting MetS in susceptible individuals.

Methods: Data was collected from a cross-sectional study conducted during the second phase of The Mashhad Stroke and Heart Atherosclerotic Disorder (MASHAD) study, which involved 1,014 participants. The presence of MetS was determined using the National Cholesterol Education Program Adult Treatment Panel III criteria.

Effect of GFRP Stirrup Confinement on the Bond Strength of GFRP-RC Beams.

The current provisions for development length in the ACI 440.11 code disregard the confinement effect provided by stirrups on the bond strength of longitudinal bars and require splice lengths that pose implementation challenges. Given the significant improvement in GFRP material properties, this study investigated the bond strength of sand-coated GFRP bars and proposed a new factor to include the effect of stirrup confinement on the bond-strength provisions.

Comparison of Complications and Outcomes of Very Low Anterior Resection (VLAR) Versus Intersphentric Resection (ISR) In Patients with Rectal Cancer.

Background: Colorectal cancer is a cancer that starts in the colon or rectum, which are part of the digestive system. Intersphincteric resection (ISR) and very low anterior resection (VLAR) are surgical procedures used in rectal malignancy. We aimed to compare postoperative complications and recurrence after VLAR and ISR techniques in patients with rectal cancer.

Autecology and determination of relationships between nutrients in soil and sage plant (Salvia eremophila Boiss.) in the south of Yazd province.

This study aims to investigate the autecology and determine the relationship between the nutritional elements in the soil and the Sage plant (Salvia eremophila Boiss.) in the south of Yazd province. The main habitats were determined, which contained various ecological characteristics.

Financial burden of lymphedema among breast cancer survivors in Iran: A qualitative study.

Background: Breast cancer-related lymphedema (BCRL) is a chronic complication of breast cancer that requires long-term management. This condition imposes significant disturbance on breast cancer survivors (BCSs) physically, emotionally, and, financially. The purpose of this study was to approach the financial burden of BCRL in Iran.

In vitro and in vivo evaluation of anti-tumorigenesis potential of nano silver for gastric cancer cells.

Silver nanoparticles (AgNP) exhibit significant cytotoxicity against MKN45 cells (IC50: 105.5 µg/mL). In vivo, AgNP at 150 mg/kg induces necrosis, reduces proliferation, and alters gene expression, presenting a promising gastric cancer treatment strategy.

Effects of resveratrol supplementation on inflammatory markers, fatigue scale, fasting blood sugar and lipid profile in relapsing-remitting multiple sclerosis patients: a double-blind, randomized placebo-controlled trial.

Objectives: Resveratrol, a polyphenol found in grapes, has been studied extensively for its potential benefits on metabolic markers and inflammation. While promising results have been observed in animal studies and some human trials, the overall evidence is mixed. Moreover, elevated inflammatory markers have been closely linked to more severe symptoms of Multiple Sclerosis (MS).

Antibiotic resistance patterns, characteristics of virulence and resistance genes and genotypic analysis of serotypes recovered from different sources.

The present study evaluated the isolates obtained from various origins in Iran. strains previously recovered and stored in the veterinary microbiology laboratory were serotyped and subjected to antibiotic susceptibility test, detection of the virulence and resistance genes by polymerase chain reaction (PCR), and genotyping by enterobacterial repetitive intergenic consensus-polymerase chain reaction (ERIC-PCR). All isolates showed resistance to erythromycin and the most resistance rates were detected for trimethoprim (86.