Publications by authors named "Seyed Amin Ayatollahi-Mousavi"

Article Synopsis
  • A rapidly emerging multidrug-resistant fungal pathogen presents a significant global health challenge, with cases reported in over 47 countries and limited treatment options due to increasing antifungal resistance.
  • Conventional detection methods are often ineffective, necessitating innovative approaches to combat infections like cutaneous candidiasis.
  • Nanoparticle-based therapies, incorporating materials such as silver and gold, show promise in treating these infections, with advancements in their mechanisms and applications potentially leading to improved clinical outcomes and lower mortality rates.
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Background: Nanotechnology has emerged as a transformative realm of exploration across diverse scientific domains. A particular focus lies on metal oxide nanoparticles, which boast distinctive physicochemical attributes on the nanoscale. Of note, green synthesis has emerged as a promising avenue, leveraging plant extracts as both reduction and capping agents.

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Due to the adverse effects associated with long-term administration of antifungal drugs used for treating dermatophytic lesions like tinea unguium, there is a critical need for novel antifungal therapies that exhibit improved absorption and minimal adverse effects. Nanoformulations offer a promising solution in this regard. Topical formulations may penetrate the upper layers of the skin, such as the stratum corneum, and release an appropriate amount of drugs in therapeutic quantities.

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Background And Objectives: The aim of this study was to investigate the antifungal potency of the moronecidin-like peptide against , and

Materials And Methods: To evaluate the antifungal effect of moronecidin-like peptide, the protocol presented in CLSI M27-A3 and CLSI M27-S4 was used and the minimum inhibitory concentration was determined.

Results: The minimum inhibitory effect of moronecidin-like peptide composition was 8 µg/ml for and and 32 µg/ml for . The MIC of nystatin was determined to be 1.

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Introduction: This study was intended to investigate the clinical features and predisposing factors of fungal keratitis (FK), as well as molecular identification and antifungal susceptibility of causative agents in Tehran, Iran.

Methods: This cross-sectional study was carried out from April 2019 to May 2021. All fungi isolates were identified using conventional methods and were confirmed by DNA-PCR-based molecular assays.

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Background: and Purpose: Myrtle (.) is a medicinal herb that plays an essential role in treating fungal infections. The present study investigated the antifungal properties of different fractions of the leaf extract against (susceptible and resistant to nystatin).

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Background: Candidiasis is the most common opportunistic oral infection and smoking is considered as one of its well-known risk factors. However, it remains unknown whether opium users are susceptible to increased oral candida colonization. The aim of the present study is to compare the prevalence rate of oral candida colonization between opium users and cigarette smokers in Kerman, Iran.

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Background And Objectives: Oral candidiasis is a serious problem for immunocompromised patients, especially patients with hematological malignancies. After becoming a systemic candidiasis it is difficult to diagnose, control and treat in individuals with hematological malignancies. The aim of this study was to diagnose candidiasis in the oral mucosa of patients with leukemias and lymphomas in a timely manner in order to prevent their progression to systemic candidiasis.

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Background And Purpose: is the most common species (sp.) isolated from fungal infections. Azole resistance in species has been considerably increased in the last decades.

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