Publications by authors named "Seyed Ali Aghapour"

Article Synopsis
  • * A 32-year-old male patient experienced recurrent severe allergic reactions (anaphylaxis) and high levels of a substance called tryptase, which indicates mast cell issues, despite not having visible skin symptoms.
  • * The condition is rare but can be serious and presents with unusual signs, highlighting the need for better diagnostic methods and treatment options to improve understanding and patient outcomes.
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Introduction And Importance: Alpha-Gal syndrome (AGS), a distinct form of mammalian meat allergy, presents unique characteristics that set it apart from typical IgE-mediated food hypersensitivities. AGS induces an allergic response typically 3-6 h post-ingestion of mammalian meat, such as beef, pork, or lamb. This prolonged reaction time differentiates AGS from other food allergies, which usually provoke a more immediate response.

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Background: Anaphylaxis is an allergic reaction which occurs with or without the stimulation of the immune system. Hymenoptera stings are common causes of anaphylaxis in the world. Skin tests are the first-line diagnostic measure for Hymenoptera anaphylaxis.

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Introduction And Importance: Symptoms similar to diseases such as Stevens-Johnson syndrome (SJS) and multisystemic inflammatory syndrome in children (MIS-C) were reported in pediatric coronavirus infections.

Case Presentation: Here, we present a 4-year-old girl with coronavirus disease 2019 (COVID-19), an earlier diagnosis of SJS, and a final diagnosis of MIS-C.

Clinical Discussion: Unlike the negative PCR test for severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), the positive serological test confirmed COVID-19.

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Article Synopsis
  • - The study evaluated the effectiveness of oral immunotherapy (OIT) for desensitizing patients with IgE-mediated egg white allergies by comparing clinical and laboratory results before and after treatment.
  • - Conducted on eight patients over six months, the results showed that all patients in the OIT group were desensitized and could tolerate 40 cc of raw egg white, unlike controls who failed the Oral Food Challenge.
  • - Findings revealed significant reductions in skin reaction and specific IgE levels post-OIT, indicating that this treatment could be a safe and effective method for managing egg allergies.
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