CXCL13 levels in cerebrospinal fluid in relapsing-remitting multiple sclerosis: The role of Borrelia in neuroinfections.

Background Objectives: This study was compared the Borrelia antibodies and chemokine ligand 13 (CXCL13) levels in cerebrospinal fluid (CSF) samples from cases diagnosed with relapsing-remitting multiple sclerosis (RRMS), radiologically isolated syndrome (RIS), and pseudotumour cerebri (PTC).

Methods: A total of 43 CSF samples were collected from patients diagnosed with RRMS, RIS and PTC. We prospectively investigated Borrelia IgG and IgM antibodies in the CSF samples of the cases by enzyme-linked immunosorbent assay (ELISA) and Western blot (WB) method, and CXCL13 levels by ELISA.

Is increased activator protein 1 in cerebrospinal fluid as a potential biomarker that distinguishes idiopathic intracranial hypertension from multiple sclerosis?

Objectives: To distinguish whether idiopathic intracranial hypertension (IIH) is a condition predisposing to multiple sclerosis (MS) or an isolated disease, the current gene transcription factor Activator Protein-1 (AP-1) was evaluated with its potential to differentiate both diseases.

Background: The aim of this study was to investigate the use of AP-1 as biomarkers for the discrimination of IIH and MS.

Methods: AP-1, TNF-α, and IL-6 protein values in the CSF of the cases were evaluated by the ELISA method.

Frequency of Lyme disease in patients with tick contact and identification of ticks from Bolu province of Turkey.

Background Objectives: Lyme disease is a multisystemic disease caused by the bacteria in the Borrelia burgdorferi sensu lato complex, which is transmitted by ticks of the Ixodes genus. Although there are seroprevalence studies and case reports of Lyme disease from various regions in Turkey, there is no widespread epidemiological research. This study aimed to determine the frequency of Lyme disease in the cases followed-up after tick contact and to examine the isolated ticks to reveal tick population from Bolu province.

Hidden realities: Food waste from servings in mini size packaging.

This paper provides data obtained from real-life measurement of the Food Waste (FW) associated with the services offering food in mini size (9-20 g) single-use packaging representing the impact of the difficulties in emptying the food from such packages and service characteristics. We collected discarded such food packages from commercial public eateries (a time-share thermal town, student canteen, and student refectory), quantified FW, and subjected data to statistical analysis regarding the eatery places, package characteristics, and food type. The results suggest that service style, packaging, and consumer wastefulness can cause 10-47 %, 3-11 %, and 5-37 % FW, respectively, indicating hidden part of the wastage iceberg from mini size food portions with vast implication on the food and relevant packaging sustainability.

Acute toxoplasmosis and antioxidant levels in the liver, kidney and brain of rats.

Toxoplasma gondii is a common protozoan parasite which causes toxoplasmosis worldwide. There are limited treatment options against T. gondii infection.

Investigation of a 6-year seropositivity of Toxoplasma gondii in Abant Izzet Baysal University Educational Research Hospital.

Objective: The aim of the present study was to determine the prevalence of Toxoplasma gondii IgG and IgM antibodies in patients who were admitted in Abant İzzet Baysal University Education and Research Hospital between January 2010 and December 2016 with a suspicion of toxoplasmosis.

Methods: Anti-T. gondii IgM and IgG antibodies and IgG avidity test determined by ELISA method in 14,262 serum samples belonging to the Abant İzzet Baysal University Education and Research Hospital were retrospectively investigated.

Determination of Anti-nuclear Antibody Pattern Distribution and Clinical Relationship.

Background And Objectives: Autoantibodies are immunglobulins occurred directly against autoantigens that are known as endogen antigens. Autoimmune disease is an occasion that the body begins a fight against its own cells and tissues. The antibodies that are created by the body against its own cell nuclei are called as anti-nuclear antibodies (ANA), and one of the methods used for detection and pattern of ANA is indirect immunofluorescence test (IIF).

Investigation of in-vitro susceptibility of multidrug-resistant Acinetobacter baumannii strains isolated from clinical specimens to tigecycline.

The management of infections due to A. baumannii is difficult because of rapidly developing resistance, however, tigecycline, a glycylcycline antimicrobial, is in use for several years. In the present study, it was aimed to determine the susceptibility rates of A.