Adipose tissue indices predict prognosis in hodgkin lymphoma.

Introduction Background: This study evaluated the impact of adipose tissue indices on prognosis of HL.

Methods: Fifty-five patients with newly diagnosed Hodgkin Lymphoma were evaluated retrospectively for association with adipose tissue indices (total abdominal tissue volume, radiodensity, subcutaneous and visceral adipose tissue SUVmax value and prognostic factors for Hodgkin Lymphoma such as IPS-3, IPS-7, stage, sedimentation, progression free and overall survival.

Results: For IPS-3, SAT SUVmax and TAAT radiodensity were significantly increased in high-risk patients (2and 3) compared to group 0 and 1.

Prognostic value of computed tomography associated body composition measurement changes in metastatic colorectal cancer patients.

Background: Sarcopenia is associated with poor prognosis in metastatic colorectal cancer (mCRC) patients.

Purpose: To investigate the prognostic value of body composition measurement changes measured by computed tomography (CT) in mCRC patients.

Material And Methods: The abdominal skeletal muscle density (SMD) and skeletal muscle (SMI) indices, as well as the visceral (VATI) and subcutaneous fat tissue (SATI) indices, were calculated by automatic segmentation method on the abdominal CT images obtained before (n = 71) and after chemotherapy (n = 52).

Correlation of F-FDG/PET SUV, SUV, MTV, and TLG with HIF-1α in Patients with Colorectal Cancer.

Objectives: Post-hypoxia hypoxia-inducible factor (HIF)-1α activation plays a vital role in colorectal cancer (CRC) angiogenesis. Although glucose metabolism is induced in some cancer types via HIF-1α, the prognostic significance of HIF-1α in CRC and its correlation with fluorinefluorodeoxyglucose (F-FDG) uptake in positron emission tomography (PET) remain controversial. This study aims to investigate the association between F-FDG/PET parameters and HIF-1α expression in CRC.

The Role of Metabolic Volumetric Parameters in Predicting Malignancy in Incidental Thyroid Nodules Detected in F-FDG PET/CT Scans.

Objectives: The metabolic activities of tumors can be calculated volumetrically during positron emission tomography/computed tomography (PET/CT) imaging using metabolic tumor volume (MTV) and total lesion glycolysis (TLG). This study aimed to evaluate the roles of MTV and TLG in predicting the malignancy risk of incidental thyroid nodules detected by PET/CT imaging.

Methods: Active metabolic areas of each section were manually drawn by region of interest to calculate the MTV of nodules, and all obtained values were then summed.

The Role of Ga-68 PSMA PET/CT Scan on Differentiating of Oligometastatic and High Risk Prostate Cancer.

Objectives: In this study, we aimed to investigate whether Ga-68 prostate-specific membrane antigen positron emission tomography/computed tomography (PSMA PET/CT) scanning is adequate to predict intermediate risk, high risk, or oligometastatic prostate cancer (PCa) as an initial staging modality.

Methods: The Ga-68 PSMA PET/CT scan images of 50 PCa patients pathologically proven by transrectal ultrasound guided biopsy were evaluated retrospectively. The association of standard uptake value maximum (SUV) value of the area with the highest PSMA expression within the primary tumor with the risk groups and metastatic burden is investigated.

Solitary Pulmonary Nodule: Morphological Effects on Metabolic Activity Assessment.

Objectives: We aimed to evaluate the effects of morphological characteristics of the solitary pulmonary nodules (SPN) on metabolic activity assessment. To the best of our knowledge, this is the first study to compare the volumetric metabolic activity parameters according to the morphologic parameters of the nodules.

Methods: In this retrospective study, F-FDG positron emission tomography and computed tomography scans performed between 2011 and 2018 were evaluated by a nuclear and diagnostic radiologist.