Publications by authors named "Sevilay Akalp-Ozmen"
Background/aim: Gastric carcinoma (GC) is a highly heterogeneous disease with many subtypes that have different morphologic and molecular characteristics. In the current study, we analyzed immunohistochemical (IHC) and in situ hybridization (ISH) features of GCs and evaluated their association with prognosis and clinicopathological features.
Materials And Methods: Three hundred cases analyzed by IHC and ISH for microsatellite stability, p53, e-cadherin, HER2, PD-L1 expression, and Epstein-Barr virus (EBV) status.
Article Synopsis
- The study investigates the impact of intrauterine devices (IUDs) on cervicovaginal smears using liquid-based cytology in a population of 5,492 patients.
- The majority of diagnoses (97.2%) were negative for malignancy, but infections were found in 54.6% of cases, with Actinomyces being the most common infectious agent (11%).
- The findings suggest that IUDs may increase the risk of genital infections by affecting the genital flora, which is particularly notable in long-term users in the Erzurum province.
Background: The pterygopalatine ganglion (PPG) and ophthalmic arteries (OpAs) have important roles in ocular autoregulation and retinal and visual functions. The relationship between PPG neuron density, OpA vasospasm, and retinal detachment in subarachnoid hemorrhage (SAH) has never been studied.
Methods: This study was conducted on 25 rabbits.
Lipomatous meningioma: A rare subtype of benign metaplastic meningiomas.
J Neurosci Rural Pract
January 2017
Lipomatous meningiomas are extremely rare subtypes of benign meningiomas and are classified as metaplastic meningioma in the World Health Organization classification. We present a 77-year-old man presented with the history of a gradually intensifying headache for the last 3 months. A right frontoparietal mass was detected on his cranial magnetic resonance imaging.
View Article and Find Full Text PDFThis study was designed to investigate whether dexmedetomidine and thiopental have cerebral protective effects after focal cerebral ischemia in rats. Thirty male Sprague Dawley rats were randomly assigned to three groups: control group (Group C, n=10), dexmedetomidine group (Group D, n=10), thiopental group (Group T, n=10). After all rats were anesthetized, they were intubated, then mechanically ventilated.
View Article and Find Full Text PDFThis study was designed to investigate whether dexmedetomidine and thiopental have cerebral protective effects after focal cerebral ischemia in rats. Thirty male Sprague Dawley rats were randomly assigned to three groups: control group (Group C, n=10), dexmedetomidine group (Group D, n=10), thiopental group (Group T, n=10). After all rats were anesthetized, they were intubated, then mechanically ventilated.
View Article and Find Full Text PDFGenetic alterations in benign, preneoplastic and malignant breast lesions.
Indian J Pathol Microbiol
February 2013
Context: The c-erbB-2 proto-oncogene is a member of the epidermal growth factor receptor family and has been associated with a more aggressive breast tumor biology and resistance to some types of treatments.
Aims: The aim is to investigate the correlation among bcl-2 and c-erbB-2 and the micronucleus (MN) formation in patients with early breast cancer (BC).
Materials And Methods: This study was conducted between May 2010 and December 2011.