Publications by authors named "Sevil Ozer-Sari"
Can serum M30 levels be utilized as an activation marker in patients with ulcerative colitis?
Rev Assoc Med Bras (1992)
September 2024
Objective: Ascertainment of disease activation is an important component of therapeutic decisions in ulcerative colitis patients and may present certain clinical challenges. The objective of this study was to determine serum levels of the M30 fragment of cytokeratin 18 and its utility as an activation marker in patients with ulcerative colitis, who are known to have increased apoptosis.
Methods: A total of 60 ulcerative colitis (30 active and 30 remission) patients aged over 18 years and 29 healthy individuals as controls were included in the study.
Article Synopsis
- Ineffective esophageal motility (IEM) is the most common esophageal motility disorder and this study explores its relationship with gastro-esophageal reflux disease by comparing patients with pathological and physiological esophageal acid reflux.
- A total of 62 patients diagnosed with IEM were assessed using high-resolution manometry and divided into two groups based on 24-hour acid monitoring results.
- Findings indicated that the physiological reflux group was younger on average and had lower rates of esophagitis compared to the pathological reflux group, although other factors such as sphincter pressures and severity of IEM were similar between both groups.
Objectives: The study aimed to investigate the subclinical involvement of cardiac functions in patients with inflammatory bowel disease (IBD), including ulcerative colitis (UC) and Crohn's disease (CD) according to their disease activity status by two-dimensional speckle tracking echocardiography (2DSTE).
Methods: This prospective study included 72 consecutive patients with IBD and 93 age- and sex-matched healthy controls (HC). All participants underwent conventional and 2DSTE assessments.
Cytomegalovirus (CMV) is an agent which exists asymptomatically in most individuals and may cause latent life-time infection following contamination. Symptomatic CMV infection develops most commonly in organ transplant recipients and in individuals who receive immunosuppressive drugs, undergo haemodialysis or have acquired immunodeficiency syndrome. The link between ulcerative colitis and CMV infection and the efficacy of antiviral therapy in these individuals have been demonstrated.
View Article and Find Full Text PDFBackground/aim: The present observational study aimed to determine the predictive value of 3-year recurrence adenoma characteristics at baseline conventional colonoscopy in patients with high-risk adenoma.Materials and methods: A total of 47 patients with high-risk adenoma at baseline colonoscopy were followed up and underwent a surveillance colonoscopy at 3 years. Correlations between adenoma recurrence and baseline adenoma characteristics (size, number, histological features, and location) were analyzed.
View Article and Find Full Text PDFBackground/aims: To evaluate the incidence of insulin resistance and metabolic syndrome (MetS) in patients with glycogenic acanthosis (GA).
Materials And Methods: Thirty patients with GA, detected upon endoscopy, and 30 age- and sex-matched control patients without GA were included in this case-control study. Patients with GA were considered group 1 and control group was considered group 2.
Background/aim: The aim of this study was to investigate the effects of celiac disease on cardiac functions using tissue Doppler echocardiography (TDE).
Patients And Methods: The study included 30 patients with celiac disease (CD) and 30 healthy volunteers. Echocardiographic examinations were assessed by conventional echocardiography and tissue Doppler imaging.
Background: Recent studies have reported an increased incidence of both aortic stiffness and left ventricular (LV) systolic and diastolic dysfunction in patients with inflammatory bowel disease (IBD). However, the association between aortic stiffness and the LV function has not been fully defined. We aimed to investigate the relationship between aortic stiffness and the LV function in IBD patients.
View Article and Find Full Text PDFBackground/aim: Celiac is predominantly a disease of the small intestine characterized by chronic malabsorption in genetically susceptible individuals who ingest grains containing. gluten, such as wheat, barley, and rye. In the present study, we evaluate left ventricular function in patients with celiac disease by using strain and strain rate echocardiography imaging.
View Article and Find Full Text PDFBackground/aims: The aim of this study was to evaluate the gastric polyps detected by endoscopy in our institution with respect to their frequency, size, anatomic location, presence of dysplasia, and histopathologic features.
Materials And Methods: Records of a total of 14,240 patients who underwent endoscopy between January 2008 and January 2012 were reviewed retrospectively. Of the 14,240 patients, 174 determined to have at least 1 histopathologically proven polyp were included in the study.
Background/aims: In Turkey, there are a limited number of studies including the characteristics of colorectal polyps, and the number of patients was too small in most of them. The aim of this study was to evaluate histological characteristics of colorectal polyps that were determined by colonoscopy and clinical features of patients who had removal of the polyp.
Materials And Methods: Patients who underwent colonoscopy were analyzed retrospectively from January 2007 to December 2011.
Aim: Celiac disease is characterized by malabsorption resulting from inflammatory injury to the mucosa of the small intestine after the ingestion of wheat gluten or related rye and barley proteins. This study aimed to identify individuals who are at risk of heart failure and increased risk for cardiovascular events by evaluating endothelial function in patients with celiac disease.
Materials And Methods: The study included 36 patients with celiac disease and 35 healthy volunteers.