Publications by authors named "Severine Badel"
Article Synopsis
- Research on chronic myelomonocytic leukemia (CMML) indicates that targeting mature malignant cells can disrupt their growth-promoting feedback loops.*
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- CMML monocytes in the blood show reduced apoptosis and are dependent on MCL1 for survival, making it a key target for treatment via the inhibitor S63845.*
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- Combining inhibitors for MCL1 and the MAPK pathway effectively triggers cell death in CMML monocytes and slows disease progression in mouse models.*
