Introduction: Reperfusion surgery following testicular ischemia is a reproductive health threatening status and may result with organ dysfunction in men. The high level of reactive oxygen species (ROS) and cease of blood flow to the testis are the most important reasons of this testicular injury. Until today, numerous experimental studies reported that antioxidants might be efficient to alleviate oxidative stress induced organ dysfunction.
View Article and Find Full Text PDFIntroduction: Hyperbaric oxygen (HBO) treatment is steadily increasing as a therapeutic modality for various types of diseases. Although good clinical outcomes were reported with HBO treatment for various diseases, the multisystemic effects of this modality are still unclear. This study aimed to investigate the renal effects of HBO experimentally.
View Article and Find Full Text PDFAnal Quant Cytopathol Histpathol
February 2016
Objective: To evaluate the histopathological and immunohistochemical effects of systemically administered nicotine on rat tongue mucosa.
Study Design: Rats were assigned to one of two groups: the experimental group received nicotine systemically (nicotine sulphate 2 mg/kg subcutaneously daily for 28 days), while the rats in the control group were administered physiological saline (1.5 mL subcutaneously for 28 days).
The aim of this study was to examine whether dexmedetomidine improves acute liver injury in a rat model. Twenty-eight male Wistar albino rats weighing 300-350 g were allocated randomly to four groups. In group 1, normal saline (NS) was injected into the lungs and rats were allowed to breathe spontaneously.
View Article and Find Full Text PDFPurpose: The aim of this study was to evaluate the effects of pomegranate (PMG) extract and carvacrol (CARV) on methotrexate (MTX)-induced oxidative stress and bone marrow toxicity.
Methods: Wistar albino rats (32 rats) were divided into four groups (n=8): Group 1 was control; Group 2 was given a single intraperitoneal injection of methotrexate (20 mg/kg); Group 3 was treated with carvacrol (73 mg/kg i.p.
Objective: Electromagnetic fields can affect intracellular Ca(2+) levels. The aim of this study was to determine the changes intracellular Ca(2+) concentration in cardiac ventricle cells of rats exposed to 0.25 mT (2.
View Article and Find Full Text PDFWe investigated the effects of disease itself and PUVA treatment on surface epithelium of conjunctiva in psoriatic patients (PP) before PUVA and after PUVA therapy and in 32 healthy volunteers. Squamous metaplasia was detected in PP both before and after PUVA therapy. We concluded that PUVA treatment applied together with preventive measures, would lead to less severe ocular side effects.
View Article and Find Full Text PDFPurpose: To evaluate the efficacy of topical cyclosporin A 0.05% in managing the symptoms of severe vernal keratoconjunctivitis (VKC).
Methods: Fifty-four children with severe VKC were included in this study.
Ann Ophthalmol (Skokie)
December 2007
We report a case of phakomatous choristoma of the lower eyelid. A 2-week-old girl was referred with a tumor of the right lower eyelid near the inner canthus, present since birth. No other abnormalities were noted.
View Article and Find Full Text PDFObjective: To investigate the toxic effects of ropivacaine on corneal endothelium by using the impression cytological method.
Methods: The study was performed between October and December 2004 in Dicle University Hospital, Diyarbakir, Turkey. Twenty-four eyes from 12 rats were used for the research.
J Pediatr Ophthalmol Strabismus
January 2004
J Pediatr Ophthalmol Strabismus
December 2003