Assessment of the Antioxidant Activity of Seed Extract and Its Protective Effect against DNA Oxidation, Protein Damage and Lipid Peroxidation.

Antioxidant properties of ethanol extract of (milk thistle) seeds was investigated. We have also investigated the protein damage activated by oxidative Fenton reaction and its prevention by seed extract. Antioxidant potential of seed ethanol extract was measured using different methods, such as lipid peroxidation, 1,1-diphenyl-2-picrylhydrazyl (DPPH) and ferric reducing power assays.

Protective effect of Diyarbakır watermelon juice on carbon tetrachloride-induced toxicity in rats.

The present study was designed to evaluate the effect of Diyarbakır watermelon (Citrullus lanatus cv. Sürme) juice on lipid peroxidation states in rat liver, kidney and brain. In vivo administration of carbon tetrachloride (CCl(4)) once a week for 28 days caused a significant elevation of serum markers of liver damage, aspartate aminotransferase (AST), alanine aminotransferase (ALT), total bilirubin (TB) and decrease in albumin when compared to the control group.