Impact of intelligent virtual and AI-based automated collimation functionalities on the efficiency of radiographic acquisitions.

Introduction: Intelligent virtual and AI-based collimation functionalities have the potential to enable an efficient workflow for radiographers, but the specific impact on clinical routines is still unknown. This study analyzes primarily the influence of intelligent collimation functionalities on the examination time and the number of needed interactions with the radiography system.

Methods: An observational study was conducted on the use of three camera-based intelligent features at five clinical sites in Europe and the USA: AI-based auto thorax collimation (ATC), smart virtual ortho (SVO) collimation for stitched long-leg and full-spine examinations, and virtual collimation (VC) at the radiography system workstation.

Feature-guided deep learning reduces signal loss and increases lesion CNR in diffusion-weighted imaging of the liver.

Purpose: This research aims to develop a feature-guided deep learning approach and compare it with an optimized conventional post-processing algorithm in order to enhance the image quality of diffusion-weighted liver images and, in particular, to reduce the pulsation-induced signal loss occurring predominantly in the left liver lobe.

Methods: Data from 40 patients with liver lesions were used. For the conventional approach, the best-suited out of five examined algorithms was chosen.

Reduction of the cardiac pulsation artifact and improvement of lesion conspicuity in flow-compensated diffusion images in the liver-A quantitative evaluation of postprocessing algorithms.

Purpose: To enhance image quality of flow-compensated diffusion-weighted liver MRI data by increasing the lesion conspicuity and reducing the cardiac pulsation artifact using postprocessing algorithms.

Methods: Diffusion-weighted image data of 40 patients with liver lesions had been acquired at 1.5 T.

Improved Visualization of Prostate Cancer Using Multichannel Computed Diffusion Images: Combining ADC and DWI.

(1) Background: For the peripheral zone of the prostate, diffusion weighted imaging (DWI) is the most important MRI technique; however, a high b-value image (hbDWI) must always be evaluated in conjunction with an apparent diffusion coefficient (ADC) map. We aimed to unify the important contrast features of both a hbDWI and ADC in one single image, termed multichannel computed diffusion images (mcDI), and evaluate the values of these images in a retrospective clinical study; (2) Methods: Based on the 2D histograms of hbDWI and ADC images of 70 patients with histologically proven prostate cancer (PCa) in the peripheral zone, an algorithm was designed to generate the mcDI. Then, three radiologists evaluated the data of 56 other patients twice in three settings (T2w images +): (1) hbDWI and ADC; (2) mcDI; and (3) mcDI, hbDWI, and ADC.

Flow-compensated diffusion encoding in MRI for improved liver metastasis detection.

Magnetic resonance (MR) diffusion-weighted imaging (DWI) is often used to detect focal liver lesions (FLLs), though DWI image quality can be limited in the left liver lobe owing to the pulsatile motion of the nearby heart. Flow-compensated (FloCo) diffusion encoding has been shown to reduce this pulsation artifact. The purpose of this prospective study was to intra-individually compare DWI of the liver acquired with conventional monopolar and FloCo diffusion encoding for assessing metastatic FLLs in non-cirrhotic patients.

Image Quality and Detection of Small Focal Liver Lesions in Diffusion-Weighted Imaging: Comparison of Navigator Tracking and Free-Breathing Acquisition.

Objectives: The aim of this study was to compare intraindividual diffusion-weighted imaging (DWI) of the liver acquired with free breathing (FB) versus navigator triggering (NT) for assessing small focal liver lesions (FLLs) in noncirrhotic patients.

Materials And Methods: Patients with known or suspected multiple FLLs were prospectively included, and spin-echo echo-planar DWI with NT and FB acquisition was performed (b-values, 50 and 800 s/mm2 [b50 and b800]). NT and FB DWI sequences with similar acquisitions times were used.

Scanned versus Fused-Reconstructed Oblique MR-Images for Assessment of the Tibiofibular Syndesmosis-Diagnostic PerFormance and Reader Agreement.

To evaluate the diagnostic performance and reader agreement of a novel MRI image fusion method enabling the reconstruction of oblique images for the assessment of the tibiofibular syndesmosis. We evaluated 40 magnetic resonance imaging examinations of patients with ankle sprains (16 with ruptures and 24 without) for the presence of anteroinferior tibiofibular ligament rupture. For all patients, we performed a fusion of standard two-dimensional transversal and coronal 3 mm PDw TSE images into an oblique-fusion reconstruction (OFR) and compared these against conventionally scanned oblique sequence for the evaluation of the tibiofibular syndesmosis.

On the dependence of the cardiac motion artifact on the breathing cycle in liver diffusion-weighted imaging.

Purpose: The purpose of this study was to investigate whether the cardiac motion artifact that regularly appears in diffusion-weighted imaging of the left liver lobe might be reduced by acquiring images in inspiration, when the coupling between heart and liver might be minimal.

Materials And Methods: 43 patients with known or suspected focal liver lesions were examined at 1.5 T with breath hold acquisition, once in inspiration and once in expiration.

Improved visualization of peripherally inserted central catheters on chest radiographs of neonates using fractional multiscale image processing.

Background: Peripherally inserted central catheters (PICCs) provide secure intravenous access for the delivery of life-sustaining medications and nutrition. They are commonly used in pediatrics. Confirmation of correct central catheter tip position is crucial.

Cardiac T2 star mapping: standardized inline analysis of long and short axis at three identical 1.5 T MRI scanners.

T2 star mapping can be applied for in vivo cardiac iron quantification. Current recommendations of imaging acquisition, post-processing and interpretation of normal values are based on old scanner types and in house software packages. A standardized comparison of short (SAX) and long axis (LAX) segments using commercially available software packages and modern scanners is lacking.

Interobserver and intermodality agreement of standardized algorithms for non-invasive diagnosis of hepatocellular carcinoma in high-risk patients: CEUS-LI-RADS versus MRI-LI-RADS.

Objectives: We compared the interobserver agreement for the recently introduced contrast-enhanced ultrasound (CEUS)-based algorithm CEUS-LI-RADS (Liver Imaging Reporting and Data System) versus the well-established magnetic resonance imaging (MRI)-LI-RADS for non-invasive diagnosis of hepatocellular carcinoma (HCC) in high-risk patients.

Methods: Focal liver lesions in 50 high-risk patients (mean age 66.2 ± 11.

Virtual Computed Tomography Colonography: Evaluation of 2D and Virtual 3D Image Quality of Sub-mSv Examinations Enabled by Third-generation Dual Source Scanner Featuring Tin Filtering.

Rationale And Objectives: To evaluate two- and three-dimensional (2D and 3D) image quality of sub-milliSievert (mSv) computed tomography (CT) colonography utilizing a third-generation dual source CT scanner featuring a tin filter.

Methods: We retrospectively evaluated 26 consecutive patients who underwent third-generation dual source CT colonography, nine with the standard-dose clinical-scan protocol (SDP) and 17 with a low-dose protocol (LDP) featuring a tin filter. Radiation dose was evaluated by volume computed tomography dose index (CTDI), dose length product (DLP), effective dose (E), and size-specific dose estimate.

Usability and Suitability of the Omics-Integrating Analysis Platform tranSMART for Translational Research and Education.

Background: Platforms like tranSMART assist researchers in analyzing clinical and corresponding omics data. Usability is an important, yet often overlooked, factor affecting the adoption and meaningful use. Analyses on the specific needs of translational researchers and considerations about the application of such platforms for education are rare.

Vascularization of the Arteriovenous Loop in a Rat Isolation Chamber Model-Quantification of Hypoxia and Evaluation of Its Effects.

Introduction: The aim of this study was to analyze the three-dimensional distribution of hypoxia in the arteriovenous (AV) loop model in rats, by examining the distribution of hypoxia-inducible factor-1 alpha (HIF-1α).

Materials And Methods: AV loops were created from the femoral artery and vein of male Lewis rats and an interpositional graft from the contralateral femoral vein. This AV fistula was embedded in a fibrin-filled isolation chamber and subcutaneously implanted into the thigh.

Accuracy and Specific Value of Cardiovascular 3D-Models in Pediatric CT-Angiography.

Computed tomography (CT)-angiography is routinely performed prior to catheter-based and surgical treatment in congenital heart disease. To date, little is known about the accuracy and advantage of different 3D-reconstructions in CT-data. Exact anatomical information is crucial.

3 Tesla Na Magnetic Resonance Imaging During Acute Kidney Injury.

Rationale And Objectives: Sodium and proton magnetic resonance imaging (Na/H-MRI) have shown that muscle and skin can store Na without water. In chronic renal failure and in heart failure, Na mobilization occurs, but is variable depending on age, dialysis vintage, and other features. Na storage depots have not been studied in patients with acute kidney injury (AKI).

Semi-automated De-identification of German Content Sensitive Reports for Big Data Analytics.

 Projects involving collaborations between different institutions require data security via selective de-identification of words or phrases. A semi-automated de-identification tool was developed and evaluated on different types of medical reports natively and after adapting the algorithm to the text structure.  A semi-automated de-identification tool was developed and evaluated for its sensitivity and specificity in detecting sensitive content in written reports.

Development and Evaluation of a Semi-automated Segmentation Tool and a Modified Ellipsoid Formula for Volumetric Analysis of the Kidney in Non-contrast T2-Weighted MR Images.

Volumetric analysis of the kidney parenchyma provides additional information for the detection and monitoring of various renal diseases. Therefore the purposes of the study were to develop and evaluate a semi-automated segmentation tool and a modified ellipsoid formula for volumetric analysis of the kidney in non-contrast T2-weighted magnetic resonance (MR)-images. Three readers performed semi-automated segmentation of the total kidney volume (TKV) in axial, non-contrast-enhanced T2-weighted MR-images of 24 healthy volunteers (48 kidneys) twice.

Evaluation of Rib Fractures on a Single-in-plane Image Reformation of the Rib Cage in CT Examinations.

Rationale And Objectives: This study aimed to evaluate the diagnostic performance of using a reformatted single-in-plane image reformation of the rib cage for the detection of rib fractures in computed tomography (CT) examinations, employing different levels of radiological experience.

Materials And Methods: We retrospectively evaluated 10 consecutive patients with and 10 patients without rib fractures, whose CT scans were reformatted to a single-in-plane image reformation of the rib cage. Eight readers (two radiologists, two residents in radiology, and four interns) independently evaluated the images for the presence of rib fractures using a reformatted single-in-plane image and a multi-planar image reformation.

Semiautomatic segmentation of the kidney in magnetic resonance images using unimodal thresholding.

Background: Total kidney volume (TKV) is an important marker for the presence or progression of chronic kidney disease, however, routine ultrasonography underestimates renal volume to a high and varying degree.

Objective: The aim of this work was to adapt and evaluate a semi-automatic unimodal thresholding method for volumetric analysis of the kidney in native T2-weighted magnetic resonance (MR) images.

Methods: In a group of healthy volunteers (n = 24; 48 kidneys), we defined a region of interest (ROI) by manually tracing the outline of the kidney in every MR image.

Computer-aided evaluation of low-dose and low-contrast agent third-generation dual-source CT angiography prior to transcatheter aortic valve implantation (TAVI).

Purpose: To evaluate the performance of computer-aided evaluation software for a comprehensive workup of patients prior to transcatheter aortic valve implantation (TAVI) using low-contrast agent and low radiation dose third-generation dual-source CT angiography.

Methods: We evaluated 30 consecutive patients scheduled for TAVI. All patients underwent ECG-triggered high-pitch dual-source CT angiography of the aortic root and aorta with a standardized contrast agent volume (30 ml Imeron350, flow rate 4 ml/s) and low-dose (100 kv/350 mAs) protocol.

Three-dimensional mapping of the arteriovenous loop model using two-dimensional histological methods.

Objectives: The aim of this study was to create an analytical tool for the three-dimensional distribution of immunohistochemically stained cells in the arteriovenous (AV) loop model of the femoral vessels of rats that fuses two-dimensional histological slides into stacks.

Methods: A total of 22 AV loops were implanted into male syngeneic Lewis rats by creating an arteriovenous fistula between the femoral artery and vein by interposing a femoral vein graft of the contralateral extremity. This fistula was embedded into an isolation chamber filled with a fibrin matrix.

Quantitative assessment of muscle injury by (23)Na magnetic resonance imaging.

Background: (23)Na magnetic resonance imaging ((23)Na-MRI) is able to measure Na(+) in vivo in humans and allows quantification of tissue sodium distribution. We now tested the utility of (23)Na-MRI technique in detecting and assessing sports-related acute muscular injury.

Case Presentation: We assessed tissue Na(+) of both lower legs with a 3T MRI scanner using a customized (23)Na knee coil.