Protective Effects of Heat-Killed against β-Amyloid-Induced Apoptosis on SH-SY5Y Cells.

A high level of β-amyloid (Aβ) in the brains of patients with Alzheimer's disease (AD) generates reactive oxygen species that induce neuronal death and DNA damage. The interaction between the gut microbiota and brain health has attracted attention in recent years. Heat-killed (hkRA) reportedly protects neurons against damage induced by oxidative stress.